30. Which of the following enzymes are required for the shown reaction?COOHCH₂CH₂C=OHS-COACoolCON CHCOOH NAD+ NADH+H+CH₂IC=0IS-COAA. a-ketoglutarate dehydrogenaseB. dihydrolipoyl dehydrogenaseC. Both A and BD. Neither A nor B

Glucose is oxidized during glycolysis and the end product (pyruvate) is converted to Acetyl CoA via…

Answered: 30. Which of the following enzymes are…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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The reaction below catalyzed by phosphoglycerate mutase is, 3-phosphoglycerate 2-phosphoglycerate an isomerization. A. В. a group transfer reaction. a reversed aldol condenstion. C. Op an oxidation reduction reaction. E. Cand D
In the 1step of the 2-step reaction shown below, which substrate/co-substrate is being oxidized? a. NADH b. B-ketoacyl-CoA c. L-B-hydroxy-acyl-CoA d. NAD+ e. H+
A patient who has been drinking large amounts of alcohol for long periods of time shows thefollowing symptoms: apathy, loss of memory, and a rhythmical to-and-fro motion of the eyeballs.Which of the following reactions are most likely to be affected in the patient? A. Conversation of pyruvate to acetyl-CoA B. Conversation of a-ketoglutarate to succinyl-CoA C. Both A and B D. Neither A nor B
The sources of the three (3) carbons in malonyl-Coa is/are: a. 1 C from C02 and 2 C from acetyl-CoA b. 1 C from HCO3- and 2 C from acetyl-CoA c. 1 C from biotin and 2 C from acetyl-CoA d. All three C from acetyl-CoA
Order the cofactors based on their use in the mechanism of the a-etogluterate dehydrogenase complex. 1. Stabilizes a carbanion due to decarboxylation 2. Allows for the splitting of the carbon skeleton from the electron pair generated in a redox reaction 3. Enzyme bond electron carrier that is part of dihydrolipoyl dehydrogenase 4. Final electron acceptor in the overall reaction catalyzed by this complex 1 2 3 4 answer choices: lipoamide, biotin, 2 Fe - 2S cluster, TPP, NAD+, FAD
3) Indicate the order in which the metabolites in citric acid cycle are produced; acetyl CoA as 1 and oxaloacetate as 9. Metabolites in Citric Acid Cycle Order Enzyme involved in the formation of the metabolite Acetyl CoA 1 Oxaloacetate 9. Succinyl SCOA Fumarate Malate Citrate Succinate a-Ketoglutarate Isocitrate
2. 'a) List the number of NADH and FADH2 equivalents formed and the corresponding number or ATP equivalents generated by mitochondrial oxidation of one molecule of CH3(CH2)12-COSCOA Number of NADH or Number of ATP Enzyme catalyzing the oxidation step FADH, formed ultimately formed B Oxidation Acyl-CoA dehydrogenase B-Hydroxyacyl-CoA dehydrogenase Citric acid cycle Isocitrate dehydrogenase a-Ketoglutarate dehydrogenase Succinyl-CoA synthetase Succinate dehydrogenase Malate dehydrogenase Total "These calculations assume that mitochondrial oxidative phosphorylation produces 1.5 ATP per FADH2 oxidized and 2.5 ATP per NADH oxidized. "GTP produced directly in this step yields ATP in the reaction catalyzed by nucleoside diphosphate kinase (p. 516). For all of the questions below, assume that respiratory activity of mitochondria is supported by CH3(CH2)12-COSCOA in the presence of excess ADP (+ P). (b) How many ATP equivalents will be generated in the presence of the inhibitor rotenone? Give a…
Answer all the following questions
What is Xi RHI NH₂+ A. following biochemic pathway? CH a-ketoglutarate coenzyme PLP aminotransferase CH₂₁₂ glutamate D. B. NH X coenzyme TPP decarboxylase 0 E. CO₂ OH
25. The AG" values for the two reactions are given. 1. 2. oxaloacetate + acetyl-CoA + H₂O → citrate + COASH oxaloacetate + acetate → citrate Enzymes for reactions 1 and 2 are citrate synthase and citrate lyase, respectively. Determine the AG" for the hydrolysis of acetyl-CoA acetyl-CoA + H₂O acetate + COASH + H+ plane een isoimorfbold bns (94) opg Vp1903 9911 AG¹⁰ ? AGO = -32.2 kJ/mol AG"=-1.9 kJ/mol
In the reaction catalyzed by malate dehydrogenase, which of the following molecules is classified as the reduced donor? a. Malate b. Oxaloacetate c. Fumerate d. FAD e. FADH2 f. NAD+ g. NADH
Which of the following molecules shown are the reduced products produced in the citric acid cycle whose reduction directly helped drive oxidation? Select all that apply. Ensure you are selecting the product forms of the molecule, which here means the reduced form, and are only considering redox reactions! Do not include the pyruvate processing steps -- just the citric acid cycle itself. A. GDP B. NADH C. FAD D. Acetyl-CoA E. NAD+ F. CoA G. FADH2 H. GTP I. QH2 J. Q

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30. Which of the following enzymes are required for the shown reaction? CH ₂ HS-COA CO₂ CH₂ IZL C=0 COOH NAD+ NADH +H+ COOH CH₂ C=O Cool S-COA A. a-ketoglutarate dehydrogenase B. dihydrolipoyl dehydrogenase C. Both A and B D. Neither A nor B