In the 1step of the 2-step reaction shown below, which substrate/co-substrate is being oxidized? a. NADHb. B-ketoacyl-CoAc. L-B-hydroxy-acyl-CoAd. NAD+e. H+ OHR-CH2-C–CH2-Ç-S-CoAL-B-Hydroxy-аcy-CoANAD+B-hydroxyacyl-CoAdehydrogenaseNADH + H+R-CH2-C–CH2-C-S-CoAB-Ketoacyl-CoAacyl-CoAacetyltransferase(thiolase)CoA-SH(C14) R–CH2-C-S-CoA + CH3-C-S-COA(C 14) Acyl-CoA(myristoyl-CoA)Acetyl -CoA

The above reaction is a part of beta oxidation of fatty acid process.

Answered: In the 1step of the 2-step reaction…

In the 1step of the 2-step reaction shown below, which substrate/co-substrate is being oxidized? a. NADH b. B-ketoacyl-CoA c. L-B-hydroxy-acyl-CoA d. NAD+ e. H+

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Question

In the 1step of the 2-step reaction shown below, which substrate/co-substrate is being oxidized?

a. NADH

b. B-ketoacyl-CoA

c. L-B-hydroxy-acyl-CoA

d. NAD+

e. H+

OH
R-CH2-C–CH2-Ç-S-CoA
L-B-Hydroxy-
аcy-CoA
NAD+
B-hydroxyacyl-CoA
dehydrogenase
NADH + H+
R-CH2-C–CH2-C-S-CoA
B-Ketoacyl-CoA
acyl-CoA
acetyltransferase
(thiolase)
CoA-SH
(C14) R–CH2-C-S-CoA + CH3-C-S-COA
(C 14) Acyl-CoA
(myristoyl-CoA)
Acetyl -CoA

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