17. The shown reaction is one of the four repeating steps during fatty acid ß-oxidation. Which of the following statements is correct for the shown reaction? B H H viftens Lutių tine CH₂-C- C-S-COA HO A A. The small molecule in box A is FAD B. It is the second oxidation reaction during B-oxidation C. Both A and B D. Neither A nor B

Biochemistry
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Chapter1: Biochemistry: An Evolving Science
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**Understanding Beta-Oxidation of Fatty Acids**

**Question 17:**
The shown reaction is one of the four repeating steps during fatty acid β-oxidation. Which of the following statements is correct for the shown reaction?

```
   A    B
    |   |
HO—CH2—C—H—C—C=O       CH2—C=O
   |    ||        ->       |     ||
   H    O                  |
 HO—H                     CH2—C—S—CoA
     |                           |
 HO—C—C=O          CO—S—CoA
    ||    |             ||    |
   O      HO      O     HO
  |       |       |        |
 HO    CoA   HO—C—S—CoA
 O       |       |
 HO—H
```

**Answer Choices:**
A. The small molecule in box A is FAD
B. It is the second oxidation reaction during β-oxidation
C. Both A and B
D. Neither A nor B

**Diagram Illustration:**

In the provided chemical reaction, two molecules are indicated by the labels 'A' and 'B':
- The molecule in box 'A' is involved in the oxidation process, which facilitates the conversion of the initial molecule to the final product.
- The molecule in box 'B' represents the product of this reaction.

**Explanation:**

In the context of fatty acid β-oxidation, the process typically involves four repeating steps:
1. Dehydrogenation, catalyzed by acyl-CoA dehydrogenase, producing FADH2.
2. Hydration, catalyzed by enoyl-CoA hydratase.
3. Dehydrogenation, this time catalyzed by β-hydroxyacyl-CoA dehydrogenase, producing NADH.
4. Thiolysis, catalyzed by thiolase, generating one acetyl-CoA and a shortened acyl-CoA.

In this reaction:
- **Box A** likely contains NAD+ (not FAD) as the coenzyme that is reduced to NADH, signifying the second dehydrogenation step in β-oxidation.
- **Box B** represents the product oxidized from the original molecule, indicating the conversion relation between the reactants and products.

**Conclusion:**
Based on the understanding of the β
Transcribed Image Text:**Understanding Beta-Oxidation of Fatty Acids** **Question 17:** The shown reaction is one of the four repeating steps during fatty acid β-oxidation. Which of the following statements is correct for the shown reaction? ``` A B | | HO—CH2—C—H—C—C=O CH2—C=O | || -> | || H O | HO—H CH2—C—S—CoA | | HO—C—C=O CO—S—CoA || | || | O HO O HO | | | | HO CoA HO—C—S—CoA O | | HO—H ``` **Answer Choices:** A. The small molecule in box A is FAD B. It is the second oxidation reaction during β-oxidation C. Both A and B D. Neither A nor B **Diagram Illustration:** In the provided chemical reaction, two molecules are indicated by the labels 'A' and 'B': - The molecule in box 'A' is involved in the oxidation process, which facilitates the conversion of the initial molecule to the final product. - The molecule in box 'B' represents the product of this reaction. **Explanation:** In the context of fatty acid β-oxidation, the process typically involves four repeating steps: 1. Dehydrogenation, catalyzed by acyl-CoA dehydrogenase, producing FADH2. 2. Hydration, catalyzed by enoyl-CoA hydratase. 3. Dehydrogenation, this time catalyzed by β-hydroxyacyl-CoA dehydrogenase, producing NADH. 4. Thiolysis, catalyzed by thiolase, generating one acetyl-CoA and a shortened acyl-CoA. In this reaction: - **Box A** likely contains NAD+ (not FAD) as the coenzyme that is reduced to NADH, signifying the second dehydrogenation step in β-oxidation. - **Box B** represents the product oxidized from the original molecule, indicating the conversion relation between the reactants and products. **Conclusion:** Based on the understanding of the β
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