7. In the ketone body pathway, both acetoacetate and B-hydroxy butyrate are produced and become additional fuel molecules for the organism. a. Define where these molecules are produced (both tissue type and location in the cell) and what tissue they "feed". b. Of these two molecules, which one is considered slightly better in delivering more energy to the target tissue? Why? c. How does acetone, another ketone body, participate in delivering fuel to target tissue? d. If acetoacetate decarboxylase enzyme was mutated and became inactive (zero enzyme activity), how would this affect the ketone pathway during these conditions: į. immediately after a meal, ii. under starvation conditions, iii. during unchecked (not being treated for) type-1 diabetes.

7. In the ketone body pathway, both acetoacetate and B-hydroxy butyrate are produced and become additional fuel molecules for the organism. a. Define where these molecules are produced (both tissue type and location in the cell) and what tissue they "feed". b. Of these two molecules, which one is considered slightly better in delivering more energy to the target tissue? Why? c. How does acetone, another ketone body, participate in delivering fuel to target tissue? d. If acetoacetate decarboxylase enzyme was mutated and became inactive (zero enzyme activity), how would this affect the ketone pathway during these conditions: į. immediately after a meal, ii. under starvation conditions, iii. during unchecked (not being treated for) type-1 diabetes.

Human Anatomy & Physiology (11th Edition)

11th Edition

ISBN:9780134580999

Author:Elaine N. Marieb, Katja N. Hoehn

Publisher:Elaine N. Marieb, Katja N. Hoehn

Chapter1: The Human Body: An Orientation

Section: Chapter Questions

Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...

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Question

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7. In the ketone body pathway, both acetoacetate and B-hydroxy butyrate are produced and
become additional fuel molecules for the organism.
a. Define where these molecules are produced (both tissue type and location in the cell)
and what tissue they "feed".
b. Of these two molecules, which one is considered slightly better in delivering more
energy to the target tissue? Why?
c. How does acetone, another ketone body, participate in delivering fuel to target
tissue?
d. If acetoacetate decarboxylase enzyme was mutated and became inactive (zero
enzyme activity), how would this affect the ketone pathway during these conditions:
į. immediately after a meal,
ii. under starvation conditions,
iii. during unchecked (not being treated for) type-1 diabetes.

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