### Citric Acid Cycle (Krebs Cycle) - Carbon Atom Origins**Question 8: The Structure of Citrate and Carbon Atoms**In this question, we analyze the structure of citrate, with carbon atoms numbered from 1 to 6. We'll also assume that carbon atoms 1 and 6 are the ones released as CO₂ during the citric acid cycle. The goal is to identify the carbon atoms in the citrate structure that originated from acetyl-CoA.#### Structure of Citrate:Here is the structure of citrate with carbon atoms numbered:``` COOH | 2 CH₂ | HO-C-3 COOH | | 4 CH₂ 6 | 5 COOH```#### Given Assumptions:- Carbon atoms 1 and 6 release as CO₂.- Determine which carbon atoms originated from acetyl-CoA.#### Answer Choices:A. 1 and 2 B. 2 and 3 C. 3 and 6 D. 3 and 4 E. 4 and 5 #### Detailed Explanation:The two carbon atoms from acetyl-CoA that are added to oxaloacetate form citrate:- **Oxaloacetate** has four carbons.- **Acetyl-CoA** contributes two carbons.- Thus, citrate, composed of six carbons, forms through their combination.Given that carbon atoms 3 and 4 are situated centrally, they are derived from acetyl-CoA.#### Correct Answer:**D. 3 and 4** These are the carbon atoms in citrate originated from acetyl-CoA.### Graphical Illustration- **Citrate Molecule:** The citrate structure is shown with carbon atoms labeled from 1 to 6. This structure is essential in studying metabolic pathways, particularly the citric acid cycle, essential for producing energy in cells. The identification of carbon atoms from acetyl-CoA aids in understanding metabolic tracing and energy production.For a visual representation, citrate can be visualized as a linear chain where each carbon is either part of a carboxyl group (COOH) or a hydroxyl group (C-OH), emphasizing its functional complexity within cellular respiration.

8. The structure of citrate is shown below. The carbon atoms in this citrate are numbered 1 to 6. Assume that carbon atoms 1 and 6 are the two carbon atoms to be given off as CO₂ in the citric acid cycle. Which carbon atoms in the shown structure are came from acetyl-CoA? 'COOH CH₂ 31 HO-³C-COOH HCH₂ Бсоон A. 1 and 2 B. 2 and 3 C. 3 and 6 D. 3 and 4 E. 4 and 5

8. The structure of citrate is shown below. The carbon atoms in this citrate are numbered 1 to 6. Assume that carbon atoms 1 and 6 are the two carbon atoms to be given off as CO₂ in the citric acid cycle. Which carbon atoms in the shown structure are came from acetyl-CoA? 'COOH CH₂ 31 HO-³C-COOH HCH₂ Бсоон A. 1 and 2 B. 2 and 3 C. 3 and 6 D. 3 and 4 E. 4 and 5

Biology 2e

2nd Edition

ISBN:9781947172517

Author:Matthew Douglas, Jung Choi, Mary Ann Clark

Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark

Chapter7: Cellular Respiration

Section: Chapter Questions

Problem 19CTQ: Nearly all organisms on Earth carry out some form of glycolysis. How does this fact support or not...

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