Genetic tests that detect mutations in the BRCA1 and BRCA2 tumor-suppressor genes are widely available. These tests reveal a number of mutations in these genes—mutations that have been linked to familial breast cancer. Assume that a young woman in a suspected breast cancer family takes the BRCA1 and BRCA2 genetic tests and receives negative results. That is, she does not test positive for the mutant alleles of BRCA1 or BRCA2. Can she consider herself free of risk for breast cancer?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Genetic tests that detect mutations in the BRCA1 and BRCA2
tumor-suppressor genes are widely available. These tests reveal
a number of mutations in these genes—mutations that have been
linked to familial breast cancer. Assume that a young woman in
a suspected breast cancer family takes the BRCA1 and BRCA2
genetic tests and receives negative results. That is, she does not
test positive for the mutant alleles of BRCA1 or BRCA2. Can she
consider herself free of risk for breast cancer?

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Introduction: The genes like the breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) genes are most generally affected in inherited breast and ovarian cancer.

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