What is the definition of Driver Mutations & Passenger Mutations? Also describe why each are informative in characterizing tumors.

Q: Briefly summarize the conventional wisdom (DNA mutation theory) of the cause of cancer. Discuss the…

A: It  proposes that successive DNA mutations in a single cell cause cancer (monoclonality). This…

Q: Personalized cancer treatments involve identifying specific pathways in an individual tumor and…

A: Introduction Cancer is defined as a condition which is characterised by uncontrolled mitosis. In…

Q: Can we identify general featurescommon to all cancer cells—such astheir production of misfolded,…

A: Cancer can be of different types depending upon the type of cells, organ affected, and stage. The…

Q: Which of the following statements are true about the rate of mutation in tumor cells (select all…

A: Chromosome rearrangements, which occur at high rates due to aneuploidy, an aberrant chromosome…

Q: How can researchers pinpoint the particular driver mutations most responsible for the cancer…

A: The development of cancer is an evolutionary process at the cellular level. Several mutations…

Q: Heterotypic interactions of tumor cells have been a fertile area for potential therapeutic…

A: Cancer is a major disorder and it causes development of abnormal cells & they divide…

Q: Describe error prone polymerases and the process of translesion synthesis (TLS). In regards to tumor…

A: Translesion synthesis (TLS) is a method of overcoming stopped replication in which particular…

Q: b) What is one reason that it is challenging to treat cancer?

A: The uncontrolled set of cell divisions give rise to cancer cells. This happens so, when the control…

Q: 27 of 41 Mutations in two important cancer-critical genes, encoding p53 and Rb, respectively, are…

A: Normal cells in cancer are continuously transformed into the tumour or malignant cells due to a…

Q: Are genome and karyotype instabilities consequencesor causes of cancer?

A: Genome ad karyotype instabilities really leads to cancer.Lets have a detailed discussion: Genome…

Q: The best strategy for treating a specific type of human tumor can depend on identifying the type of…

A: Part A. IFS are the ones that provide abundant buffering system in order to protect against…

Q: Briefly describe the structural variability of cancer genomes.

A: The loss or drift may result in the occurrence of cancer in breast cancer. Breast cancer is define…

Q: Give Examples of oncogenic mutations?

A: An oncogene is a gene that has the potential to cause cancer when these genes are mutated or…

Q: What separates cancer cells from normal cells?

A:

Q: The following are drugs that act as anti-tumor agents and are often used as part of chemotherapeutic…

A: Drug - adriomycin, target organ - intercalates between DNA base. MECHANISM OF ACTION:Doxorubicin…

Q: Create a graph as a better way to display the data in the table 2) Determine which mutations (5q,…

A: Tumorigenesis or oncogenesis refers to the initial formation of cancer, where normal cells is prone…

Q: Explain whether a cancercausing mutation in a tumorsuppressor gene, such as p53,is more likely to be…

A: Tumor suppressor gene regulates a cell during the cell division and replication. If cells grows…

Q: What types of evidence indicate that cancer arises from genetic changes?

A: Cancer is a disorder in which abnormal cells divide irrepressibly and destroy the tissues of the…