Personalized cancer treatments involve identifying specific pathways in an individual tumor and selecting drugs that are effective for the modified pathways. One way to do this is to take culture cells from a biopsy of a specific paient and test the effects of a battery of drugs on the patiets cells in culture. How might heterotypic interactions complicate this strategy? How might cells be cultured differently to minimize these complications (limit 5-6 sentences)?

Q: Briefly summarize the conventional wisdom (DNA mutation theory) of the cause of cancer. Discuss the…

A: It  proposes that successive DNA mutations in a single cell cause cancer (monoclonality). This…

Q: Describe the logistics of how these electrochemical sensors are used in cancer detection/ diagnosis…

A: Introduction :- Cancer is a group of diseases characterized by the uncontrolled growth and spread of…

Q: 3. After reading the scenario, fill in the table with the following information: A cancer biologist…

A: Introduction :  LCancer is brought on by the uncontrolled division of abnormal cells in a body…

Q: How is an inmortal cancer cell line different from a regular cancel cell line ?

A: Cancerous cells : In our body cell division and differentiation is a highly regulated and controlled…

Q: #1)  Hyperplastic growth are not cancerous yet but show a higher than normal proliferation rate.…

A: ANSWER) TRUE Hyperplastic growth is the increase in the number of cells and therefore the…

Q: There are usually ethical concerns when the topic of biotechnology is discussed.  The use of…

A: Ethical concerns related to human tissue use in research.

Q: Which of the following statements are correct about cancer drug resistance (select all that apply)?

A: Cancer drug resistance is the acquired after treatment effects that many of the Cancer Patients…

Q: Discuss the behaviors of cancer cells that maydifferentiate their growth from that of normal cells.

A: Cell growth or cell proliferation is a process by which the cells grow in number through multiple…

Q: What is meant by the "two-hit" model of cancer development? Describe this theory in detail and…

A: Two-hit hypothesis : The "two-hit" hypothesis or model was first proposed by geneticist Alfred…

Q: Why is it harder to develop a drug that targets a tumor suppressor gene compared to an oncogene…

A: Uncontrolled cell division in the cells may result into the tumor formation. Sometimes the cells may…

Q: With regard to cancer cells, which of the following are true? DA Cancer cells are clonal, meaning…

A: Ans: Cancer: It is the uncontrolled growth of cells in response to or due to mutation.

Q: Download and read the attached review article…

A: Some cancer patients would only need one operation. Many patients, on the other hand, undergo a…

Q: What does the 20th chromosome do?

A: Chromosomes are thread-like structure, which are composed of nucleic acids and protein. They are…

Q: Sequencing Place the following in order of how they happen in the body. Metastasis Reproduction of…

A: Answer:

Q: What is necessary for the Cancer diagnosis to be made? What information and additional factors…

A: Cancer is class of disease which dis[play uncontrolled cell growth or tissue beyond normal limits.…

Q: 1. Based on your figure of the cells under the microscope in the picture (10x magnification) , list…

A: The extracellular matrix (ECM) is an intricate network consisting of extracellular macromolecules…

Q: In a cancer research lab,normal cells have specific biomarker AAP1 while cancer cell display SSR1…

A: Cancer is the uncontrolled growth of abnormal cells in a body. Cancer arises as a result of…

Q: Cancer is a major public health problem.  Both inherited genes and environmental factors play a role…

A: Cancer has become a major global health issue for some time. Cancers occur by environmental…

Q: In your own words, explain how cancer cells differ from normal cells in regard to the following:…

A: Cancerous cells are uncontrolled cells that keep on dividing and proliferating to form an abnormal…

Q: Describe some of the recent ways of preventing or curing cancer in the country like the use of…

A: Cancer is a condition where there is uncontrollable abnormal cells growth invading the surrounding…

Q: Discuss why cancer treatment may involve a combinationof chemotherapy, radiation therapy, and…

A: For some cancers, the best approach is a combination of cancer surgery, radiation therapy and…

Q: Name the six fundamental properties of malignant tumours. Which of these properties are amenable to…

A: Malignant cells grow uncontrollably, invading nearby tissues and spreading to other parts of the…

Q: Out of these 8 hallmarks ( sustaining proliferative signaling, evading growth suppressors, resisting…

A: The cells multiply by cell division. It is a controlled process for the growth and development of…

Q: Describe three popular methods for silencing tumor-suppressor genes.

A: Introduction Tumor suppressor genes are those that slow down the division and development of cells.…

Q: Explain Three mechanisms for viral induction of cancer.

A: Cancer is not a single disease, its group of disease. Cancer causes are more, more risk disease,…

Q: Discuss how genetic tests and tumor marker tests maybe used to prevent cancer.

A: Genetic test is the use of laboratory test to look for genetic variations associated with disease.

Q: Name and describe 5 properties of cancerous or tumor cells from patients(in vivo) and of cancerous…

A: Cancerous cells are abnormal cells that grow uncontrollably, invade surrounding tissues, and can…

Q: Which of the following is NOT an example of a fail-safe mechanism that prevents the irregular cell…

A: Uncontrolled cell division results in the development of a tumor or cancer. There are many factors…

Q: Explain the importance of cell receptors in breast cancer therapy.

A: Cell receptors are the type of proteins which are present in the cell membrane and these proteins…

Q: Which of the following statements are correct about tumors and metastasis (select all that apply)?…

A: Tumor is an abnormal mass of cells which grow and divide more than their requirement or they do not…

Q: What is a method some tumors use to evade restriction of their growth by secreting substances that…

A: Cells are the part of human body which grows and divide to make new cells. They are the basic…

Q: A question that puzzled scientists was that how chemical carcinogens caused cancer. The experiment…

A: This is a hybridoma technology where a cancerous cell mixed up with a normal myoloma cell and…

Q: In a patient diagnosed with a Squamous cell carcinoma that exhibits high Base Excision Repair…

A: PARP1 inhibitors are a type of targeted cancer therapy that exploit the concept of synthetic…

Q: O The RB gene is likely hypomethylated in this individual O This individual is at much higher risk…

A: Retinoblastoma is an ocular malignancy occurring during childhood, which can affect both eyes and is…

Q: After reading the scenario,fill in the table with the following information.

A: Scientific research methods involve following step-by-step procedures and approaches to research…

Q: What is/are the role/s of molecular techniques in understanding cancer? Cite some references from…

A: In cancer, cells grow abnormally. Cancer is not one disease. It is a group of diseases. The…

Q: why didn't you choose to isolate some adult stem cells and what's the best cellular potency level…

A: Stem cell is a special human cell with unique ability to develop into many different cell types from…

Q: Looking at Figure 1, what did Romansik et al. (2007) find regarding the relationship between the…

A: The mitotic index is a measure of the number of cells in a tissue sample that are undergoing cell…

Q: Excessive angiogenesis and reduced apoptosis are two of the six characteristics that define…

A: Angiogenesis:  Angiogenesis refers to the process of the growth and development of new blood vessels…

Q: Briefly outline the location, isolation , characterisation, benefits, and limitations of adult stem…

A: The definition of a stem cell is a unspecialized cell that can renew itself and, in some cases,…

Q: Which of the following would be considered a commonly acquired characteristic of cancer cells?…

A: Cancer cells exhibit a range of distinct characteristics. These characteristics, often referred to…

Q: Choose the letter of the best match from the following. A. Spindle Checkpoint B. Checkpoint to look…

A: G1= C.Time of the most cell growth(longest and first phase of the cell cycle ) S=E. Duplicate copy…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.