Figure 1. + Η NaOH, H2O (pKa = 15) heat H + "Да H A pKa = 20 B pKa = 17 D The aldol condensation reaction in Figure 1 is an amazing example of how unfavorable equilibrium processes can be manipulated to generate product in good yields. In this case, the major product is the self-condensation product, D. The next most abundant product is the crossed aldol product, C. There are 2 other less favorable products that could form but are not shown in Figure 1. Draw a plausible electron pushing mechanism to show how product C is formed. Remember, if an alow Stans mom an electron pair, you must explicitly draw those electrons in.
Figure 1. + Η NaOH, H2O (pKa = 15) heat H + "Да H A pKa = 20 B pKa = 17 D The aldol condensation reaction in Figure 1 is an amazing example of how unfavorable equilibrium processes can be manipulated to generate product in good yields. In this case, the major product is the self-condensation product, D. The next most abundant product is the crossed aldol product, C. There are 2 other less favorable products that could form but are not shown in Figure 1. Draw a plausible electron pushing mechanism to show how product C is formed. Remember, if an alow Stans mom an electron pair, you must explicitly draw those electrons in.
Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter17: Metabolism: An Overview
Section: Chapter Questions
Problem 14P
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Transcribed Image Text:Figure 1.
+
Η
NaOH, H2O (pKa = 15)
heat
H
+
"Да
H
A
pKa = 20
B
pKa = 17
D
The aldol condensation reaction in Figure 1 is an amazing example of how unfavorable equilibrium processes can be
manipulated to generate product in good yields. In this case, the major product is the self-condensation product, D. The
next most abundant product is the crossed aldol product, C. There are 2 other less favorable products that could form but
are not shown in Figure 1.
Draw a plausible electron pushing mechanism to show how product C is formed. Remember, if an
alow Stans mom an electron pair, you must explicitly draw those electrons in.
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