The Entner-Doudoroff pathway is an alternate pathway from glucose to pyruvate found inmicroorganisms and some plants.Glucose-ATPADPGlu-6-P-NADPNADPH/H*6-P-Glucono-5-Lacton-H₂O6-P-Gluconat➤H₂OKDPG3-3-3-88-8➤ H₂O-ADPATP1,3-bPGNAD*; PNADH/H*-ADPATPPyrCircle the steps that are the same as glycolysis, draw a box around those that are from thepentose phosphate pathway. Draw triangles around those that are different.KDPG looks like this°OHHOOHOHKDPGLook at the products of the pathway. Compare the ATP and reducing equivalents producedby this pathway and the "normal" glycolysis and explain under what conditions thispathway might be active rather than the standard glycolytic pathway.

Approach to solving the question:Glycolysis and the Entner-Doudoroff (ED) pathway yield different…

Answered: The Entner-Doudoroff pathway is an…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Which of the following monosaccharide phosphates is NOT produced in the pentose phosphate pathway? O seduheptulose-7-phosphate O mannose-6-phosphate O ribose-5-phosphate O erythrose-4-phosphate
In glycolysis, the KM value of hexoquinase is 0.04 mM. At physiological conditions, the cellular concentration of glucose is between 4 mM to 15 mM. According with this information, which of the following statements is true (Choose all that are correct) The enzyme has a low affinity for its substrate The enzme is working at its maximum velocity The phosphorilation of glucose is very slow The small value of KM assures that glycolysis will continue even when the concentration of glucose drops below 4 mM. The hexoquinase is saturated with glucose
The following Michaelis-Menten plot shows the response of phosphofructokinase-1 (PFK-1), an enzyme in the glycolytic pathway, to the presence of ATP and AMP. Based on the data below, which of the following statements apply? Select all that apply. No inhibitors (low (ATP)) 1 mM ATP + 0.1 mM AMP 1 mM ATP 1.0 2.0 (Fructose-6-phosphate) mM Fig. : Regulation of PFK activity AMP is an allosteric modifier that enhances the binding of the substrate fructose 6-phosphate а. O b. AMP is an allosteric modifier that reduces the binding of the substrate fructose 6-phosphate ATP is an allosteric modifier that reduces the binding of the substrate fructose 6-phosphate O c. O d. ATP is an allosteric modifier that enhances the binding of the substrate fructose 6-phosphate Phosphofructokinase activity
Below is an image of the Krebs cycle: acetyl-CoA oxaloacetate COASH H20 NADH NAD* H20 malate citrate fumarate isocitrate FADH2 NAD* CO2 FAD АТР NADH + ADP succinate GTP NAD+ a-ketoglutarate H20 GDP NADH + CO2 COASH succinyl CoA COASH Consider the conversion of succinate to fumarate, which is coupled with the production the electron carrier FADH2. If this reaction was NOT coupled with the production of FADH2 (and only catalyzed the conversion of succinate to fumarate), how would this impact ATP production through cell respiration? OATP production would stop because no high energy electron carriers would be produced ATP production would still occur, but there would be a much lower ATP yield because a large number of electron carriers are no longer being made ATP production would stop because without FADH2 we will no longer have electrons moving through the electron transport chain ATP production would still occur, but there would be a slightly lower ATP yield because a small number of…
In the regulation of glycogen phosphorylase, which of the following statements is true? The inactive T form becomes activated when it gets dephosphorylated. The active R form is inhibited by glucose. Phosphoprotein phosphatase catalyzes the attachment of a phosphate group to a Ser residue in glycogen phosphorylase. The allosteric modulator glucose-6-phosphate promotes the conformation change from inactive T state to active R state.
What is the first cofactor to accept electrons from pyruvate in the Pyruvate dehydrogenase complex? Thymine pyroposphate lipoyllysine FAD NAD⁺
Each of the following enzymes are similar in that they are all regulation points for the pathway/cycle they operate in ... except for one enzyme. Which of the following is not a regulated enzyme? Pyruvate carboxylase Transketolase Glycogen phosphorylase Citrate Synthase Phosphofructokinase Acetyl CoA carboxylase 888888
Under anaerobic conditions, following the radiolabel at carbon-2 of pyruvate, in which molecule does the carbon label ultimately end up so that it can be taken up by the muscle cell and used for metabolism? Lactate C-2 Glucose C-2 and C-5 Acetyl- CoA C-2 Glucose C-1 and C-6 CO2 Pyruvate C-2
Arsenate can replace inorganic phosphate in the reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase, causing glyceraldehyde-3-phosphate to be directly converted to 3-phosphoglycerate(NADH is still formed). Which of the following is absolutely true in case of arsenate poisoning -Glycolysis will stop - Glycolysis will still proceed with no net ATP gain - Glycolysis will not generate any form of energy - Glycolysis will still proceed, but with a net consumption of ATP - Glycolysis will proceed with lactate as end product
What are the main products of the pentose phosphate pathway? (both branches, select all that apply) Ribose-5-phosphate NADPH Xylulose-5-phosphate glyceraldehyde-3-phosphate Glucose-6-phosphate
The AG of the reaction C6H12O6 + 60₂ --> 6CO₂ + 6H₂O is -686 kcal/mol glucose oxidized. The AG of the reaction ADP + P₁ --> ATP + H₂O is + 7.3 kcal/mol ATP synthesized. The oxidation of glucose can be coupled to the synthesis of ATP. If the coupling is 50% efficient, how many molecules of ATP can be synthesized per molecule of glucose oxidized? Round your answer to the nearest whole number.
When the cells of our body are in dire need to synthesize Ribose 5 phosphate and it has already enough supply of NADPH, reverse non oxidative pathway of the HMP shunt pathway takes place. If the cell has 10 glucose 6 phosphate molecules, how many of these would be converted to Fructose 6 phosphate and how many to form glyceraldehyde 3 phosphate respectively to synthesize maximum number of Ribose 5 phosphate? 8:2 2:8 4:6 6:4

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