A Results: Gene targeting of ES cells chromosome 1 lefty2 wild type allele targeting vector 16 kb lefty2 leftyl HH HI 5'probe X H H HH L Flanking DNA homology -ve Selectable marker HHH neo DT] +ve Selectable marker 12 kb H targeted allele B diagnostic restriction fragment length H for recombinant H H H neo Result: heterozygous and homozygous mutants 1kb 16 kb 12 kb

A Results: Gene targeting of ES cells chromosome 1 lefty2 wild type allele targeting vector 16 kb lefty2 leftyl HH HI 5'probe X H H HH L Flanking DNA homology -ve Selectable marker HHH neo DT] +ve Selectable marker 12 kb H targeted allele B diagnostic restriction fragment length H for recombinant H H H neo Result: heterozygous and homozygous mutants 1kb 16 kb 12 kb

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter13: An Introduction To Genetic Technology

Section: Chapter Questions

Problem 20QP: Analyzing Cloned Sequences A base change (A to T) is the mutational event that created the mutant...

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