2 2 1.5 1.0 0.67 5. (15 points) An individual comes into your clinic with a phenotype that resembles Down's syndrome. You perform CGH by labeling the patient's hobe DNA red and her mother's DNA green. Plot the expected results of the Red:Green ratio if: A. The cause of the syndrome was an inversion on one chromosome 21 in the child 0.5 1.5 1.0 0.67 0.5 21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19 B. The cause of the syndrome was a duplication of the material between 21q14 and 21q18 on one chromosome in the child 21 p 123456789 10 CEN q 12345678910 11 12 13 14 15 16 17 18 19 C. The mother carried a balanced translocation that segregated by adjacent segregation in meiosis I and resulted in a duplication in the child of the material distal to the translocation breakpoint at 21q14. 1.5 1.0 0.67 0.5 21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19 mom seal blo

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter12: Mendel's Experiments And Heredity
Section: Chapter Questions
Problem 29CTQ: Why is it more efficient to perform a test cross with a homozygous recessive donor than a homozygous...
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2
2
1.5
1.0
0.67
5. (15 points) An individual comes into your clinic with a phenotype that
resembles Down's syndrome. You perform CGH by labeling the patient's
hobe DNA red and her mother's DNA green. Plot the expected results of the
Red:Green ratio if:
A. The cause of the syndrome was an inversion on one chromosome 21 in the child
0.5
1.5
1.0
0.67
0.5
21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19
B. The cause of the syndrome was a duplication of the material between 21q14 and
21q18 on one chromosome in the child
21 p 123456789 10 CEN q 12345678910 11 12 13 14 15 16 17 18 19
C. The mother carried a balanced translocation that segregated by adjacent
segregation in meiosis I and resulted in a duplication in the child of the material
distal to the translocation breakpoint at 21q14.
1.5
1.0
0.67
0.5
21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19
mom
seal blo
Transcribed Image Text:2 2 1.5 1.0 0.67 5. (15 points) An individual comes into your clinic with a phenotype that resembles Down's syndrome. You perform CGH by labeling the patient's hobe DNA red and her mother's DNA green. Plot the expected results of the Red:Green ratio if: A. The cause of the syndrome was an inversion on one chromosome 21 in the child 0.5 1.5 1.0 0.67 0.5 21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19 B. The cause of the syndrome was a duplication of the material between 21q14 and 21q18 on one chromosome in the child 21 p 123456789 10 CEN q 12345678910 11 12 13 14 15 16 17 18 19 C. The mother carried a balanced translocation that segregated by adjacent segregation in meiosis I and resulted in a duplication in the child of the material distal to the translocation breakpoint at 21q14. 1.5 1.0 0.67 0.5 21 p 12345678910 CEN q 123456789 10 11 12 13 14 15 16 17 18 19 mom seal blo
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