19. Substances A and B have affinity for the same receptor but substance B is a full agonist whereas A lacks efficacy. When co-administered with A, the efficacy of B is reduced and remains the same when the dose of B is doubled. What type of ligand is substance A? a) Partial agonist b) Inverse agonist c) Non-competitive antagonist d) Competitive antagonist e) Positive allosteric modulator

Basic Clinical Lab Competencies for Respiratory Care: An Integrated Approach
5th Edition
ISBN:9781285244662
Author:White
Publisher:White
Chapter14: Introduction To Respiratory Care Pharmacology
Section: Chapter Questions
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19. Substances A and B have affinity for the same receptor but substance B is a full agonist whereas A lacks
efficacy. When co-administered with A, the efficacy of B is reduced and remains the same when the dose
of B is doubled. What type of ligand is substance A?
a) Partial agonist
b) Inverse agonist
c) Non-competitive antagonist
d) Competitive antagonist
e) Positive allosteric modulator
Transcribed Image Text:19. Substances A and B have affinity for the same receptor but substance B is a full agonist whereas A lacks efficacy. When co-administered with A, the efficacy of B is reduced and remains the same when the dose of B is doubled. What type of ligand is substance A? a) Partial agonist b) Inverse agonist c) Non-competitive antagonist d) Competitive antagonist e) Positive allosteric modulator
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