Chapter 9, Problem 7Q

Summary Introduction

To review:

The reason for the occurrence of lactic aciduria.

Introduction:

Pyruvate carboxylase deficiency (PCD) is a disease in which the enzyme pyruvate carboxylase is defective or nonfunctional. The main function of this enzyme is to produce oxaloacetate from pyruvate. An individual with nonfunctional PCD urinates high levels of lactic acid. This is known as lactic aciduria.