Biochemistry, The Molecular Basis of Life, 6th Edition
Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 7, Problem 10RQ
Summary Introduction

To review:

Definition of the following terminologies:

1) Glycoconjugate

2) Glycolipid

3) Proteoglycan

4) Glycoprotein

5) Sugar code

Introduction:

Living organisms are composed of a largevariety of carbohydrates such as cellulose, glycogen, starch, to name a few. Glycoconjugates are the compounds formed by the linking of carbohydrates to either proteins or lipids. The carbohydrate-protein conjugate can be either proteoglycans or glycoproteins. They play a crucial role in basic cellular functioning.

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The AG" of hydrolysis (ATP + H2O --> ADP + Pi) is -31.0 kJ/mol. Answer the following questions assuming that the steady-state concentrations in the cell are as indicated below. (Note: Steady-state refers to a non-equilibrium situation that exists due to a balance between reactions that supply and remove these substances.) [ADP] = 0.40 mM, [ATP] = 4.0 mM, and [Pi] = 40.0 mM a) Calculate the equilibrium constant for this reaction. b) What would the AG' for ATP hydrolysis be in the cell? c) Is this reaction at equilibrium in the cell? Briefly explain your answer.
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