Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 4, Problem 7QP
Use the following information to respond to the three questions posed below: (1) The proband (affected individual who led to the construction of the pedigree) exhibits the trait. (2) Neither her husband nor her only sibling, an older brother, exhibits the trait. (3) The proband has five children by her current husband. The oldest is a boy, followed by a girl, then another boy, and then identical twin girls. Only the second oldest fails to exhibit the trait. (4) Both parents of the proband show the trait.
- a. Construct a pedigree of the trait in this family.
- b. Determine how the trait is inherited (go step by step to examine each possible pattern of inheritance).
- c. Can you deduce the genotype of the proband’s husband for this trait?
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Please answer both questions in detail. Correct answers are highlighted.
Draw a pedigree chart for the following scenarios and answer the questions:
1. A woman's sister has cystic fibrosis, a disease caused by recessive genes.
Neither of her parents has the disease. What chance is there that her mother
is a carrier (heterozygous) for the trait? What chance is there that the woman
herself is a carrier for the trait?
2. Huntington's disease is a degenerative disease of the nervous system which
does not show up until age 40. It is caused by a dominant gene. John's father
just began to show the symptoms. What is the chance that John will have the
disease?
3. The pedigree below shows the blood types of some individuals. List all of
the possible genotypes of the individuals and determine the blood group AND
genotype of the missing blood groups.
B
AB
Examine the pedigree and answer the following questions; shaded individuals show the trait; genotypes are all unknown.
The individual marked with the question mark is of an unknown genotype but does have the trait.
A. What mode of inheritance is the most likely for this trait, autosomal recessive or autosomal dominant? State your rationale for full credit.
B. What is the genotype of the individual marked with the question mark? (Heterozygous, homozygous, or unknown)
Chapter 4 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 4.3 - Does a pedigree drawn from the available...Ch. 4.3 - Prob. 2EGCh. 4.7 - Did the fact that Prince Albert and Queen Victoria...Ch. 4.7 - Which members of the pedigree could have been...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...
Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Use the following information to respond to the...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - A proband female with an unidentified disease...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Prob. 12QPCh. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 16QPCh. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 23QPCh. 4 - Prob. 24QPCh. 4 - Variations in Phenotype Expression Define...Ch. 4 - Prob. 26QPCh. 4 - Variations in Phenotype Expression A genetic...Ch. 4 - Variations in Phenotype Expression Explain how...
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