Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Textbook Question
Chapter 4, Problem 5QP
Analysis of Autosomal Recessive and Dominant Traits
- a. What pattern of inheritance is suggested by the following pedigree?
- b. For genotype assignment, assume that the pedigree is for an autosomal dominant trait and that the affected male in the first generation is heterozygous. Assign genotypes to all other individuals in the pedigree.
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Examine the pedigree and answer the following questions; shaded individuals show the trait; genotypes are all unknown.
The individual marked with the question mark is of an unknown genotype but does have the trait.
A. What mode of inheritance is the most likely for this trait, autosomal recessive or autosomal dominant? State your rationale for full credit.
B. What is the genotype of the individual marked with the question mark? (Heterozygous, homozygous, or unknown)
Examine the pedigree and answer the following questions; shaded individuals show the trait; genotypes are all unknown.
The individual marked with the question mark is of an unknown genotype but lacks the trait.
A. What mode of inheritance is the most likely, autosomal recessive or autosomal dominant? State your rationale for full credit.
B. What is the genotype of the individual designated with the question mark? (Heterozygous, homozygous, or unknown).
C. What are the genotypes of the parents in generation I? (Heterozygous, homozygous, or unknown).
D. What are the genotypes of the three children of generation IV? (Heterozygous, homozygous, or unknown).
A. Identify the pattern of inheritance in the pedigree below.
B. Provide two pieces of evidence that you used to come to this conclusion.
C. Identify the genotypes of individuals II-1 and III-2 (at the arrows)
Chapter 4 Solutions
Human Heredity: Principles and Issues (MindTap Course List)
Ch. 4.3 - Does a pedigree drawn from the available...Ch. 4.3 - Prob. 2EGCh. 4.7 - Did the fact that Prince Albert and Queen Victoria...Ch. 4.7 - Which members of the pedigree could have been...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree analysis is a fundamental tool for...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Pedigree Analysis Is a Basic Method in Human...
Ch. 4 - Pedigree Analysis Is a Basic Method in Human...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Use the following information to respond to the...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - A proband female with an unidentified disease...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Prob. 12QPCh. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 16QPCh. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of Autosomal Recessive and Dominant...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Analysis of X-Linked Dominant and Recessive Traits...Ch. 4 - Prob. 23QPCh. 4 - Prob. 24QPCh. 4 - Variations in Phenotype Expression Define...Ch. 4 - Prob. 26QPCh. 4 - Variations in Phenotype Expression A genetic...Ch. 4 - Variations in Phenotype Expression Explain how...
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- the pedigree below shows the inheritance of a newly identified eye color gene. Assume 100% penetrance and expressivity. Use the pedigree to find: 1. Identify the mode of inheritance (either autosomal dominant, or autosomal recessive) 2. Argue why your mode of inheritance must be correct. Your argument should cite specific individuals from the pedigree. (For example, the top left individual is person I-1).arrow_forwardBackground Information: Autosomal Dominant/Recessive- The trait is encoded by a single genetic locus with two segregating alleles: One dominant (A) and one recessive (a). The locus is not on a sex chromosome, and is not linked to any other trait unless specified.Autosomal Codominance- This mode is the same as Autosomal Dominant/Recessive, except that neither allele isdominant or recessive and heterozygous individuals have a distinct phenotype. X-linked Dominant/Recessive - The trait is encoded by a single genetic locus with two segregating alleles: One dominant (A) and one recessive (a). The locus is located on the X-chromosome, and is not linked to any other trait unless specified.X-linked Codominance- This is the same as X-linked dominant/recessive, except that heterozygous females (twocopies of the X-chromosome) experience a distinct phenotype relative to females that are homozygous for either of the two alleles. Males will be segregating with two phenotypes (because they only have…arrow_forwardPLEASE ANSWER PART C.arrow_forward
- Please consider the following pedigree. Assume that people who marry in to the family do not carry the allele unless otherwise indicated. Assume complete penetrance. image attached a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR)(ii) an autosomal dominant allele (AD)(iii) a X-linked recessive allele (XR)(iv) a X-linked dominant allele (XD) b. Provide a set of parents that definitively supports your answers in (a).arrow_forwardGiven the following pedigree added. What questions are true and false?arrow_forwardPls answer the very last question. “ suppose that lll-2 and lll-5 were to have a child. What is the probability that their first child will be have the disorder?”arrow_forward
- Using the pedigree chart attached: Above is a pedigree for colorblindness. Based on the pedigree, is the disease dominant or recessive and is it sex-linked or autosomal? Why? Furthermore, what is the probability that 18 on this chart is affected but the condition, and what is the probability that 18 is a carrier? Why? Are the probability of being a carrier and an affected individual different? Why?arrow_forwarda. On the basis of this pedigree, what is the most likely mode of inheritance for the disease? Explain your reasoning. b. Based your answer to part a, give the most likely genotypes for all family members in the pedigree.arrow_forwardCodominance pattern of inheritance: Two equally dominant alleles (IA and IB) and one recessive (i)Fill in the chart with the missing information. Remember, blood genotypes are indicated with IA IB and i alleles.#1. a. Write down all of the possible genotypes possible for human blood type. How many?b. evaluate the difference between genotype and phenotype by filling in the table. BLOODPHENOTYPE Possible Genotype(s Can donate blood to Can receive blood from: O O AB AB (universal recipient) A O,A B AB, Barrow_forward
- Please explain I don’t think this is autosomal dominant as female are more affected than male and please explain B part of the question well.arrow_forwardPlease consider the following pedigree. Assume that people who marry in to the family do not carry the allele. Assume complete penetrance. I II III 3 IV 1 2 a. Is it possible for the inheritance pattern for the trait illustrated in this pedigree to be as a result of each of the following? Answer yes or no. (i) an autosomal recessive allele (AR) (ii) an autosomal dominant allele (AD) (iii) a X-linked recessive allele (XR) (iv) a X-linked dominant allele (XD) b. Based strictly on the characteristic patterns of inheritance that define the four different options in (a), give a definitive motivation for the most likely mode of inhertance.arrow_forwardPlease help a bit confused, don't need detailed response just an understanding of the ideaarrow_forward
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