Please help me to draw this by hand. In as much detail as possible, hand draw a schematic diagram of the hypothalamic-pituitary-gonad (HPG) axis in the human female. Be sure to include all the relevant structures and hormones. You must define all abbreviations the first time you use them. Please include (and explain) the feedback loops.

Please help me to draw this by hand. In as much detail as possible, hand draw a schematic diagram of the hypothalamic-pituitary-gonad (HPG) axis in the human female. Be sure to include all the relevant structures and hormones. You must define all abbreviations the first time you use them. Please include (and explain) the feedback loops.

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter26: Medications Used In Treatment Of Endocrine Disorders

Section: Chapter Questions

Problem 7RQ

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________ Although the incidence of neural tube defects in the United States declined post-folic acid fortification, some women are still at risk. Which of the following options represents a risk group for inadequate folate status and a neural tube defect affected pregnancy? a. Non-Hispanic Black women b. Non-Hispanic White women c. Asian Americans d. Hispanic Americans
Premenstrual syndrome (PMS) can include mood swings, fluid retention (edema), anxiety, backache and joint pain, food cravings, and other symptoms. PMS usually develops after ovulation and lasts until just before or just after menstruation begins. Although the precise cause of PMS is unknown, it seems clearly related to the cyclic production of ovarian hormones. After reviewing Figure 16.3, suggest which hormonal changes may trigger PMS. Figure 16.3 Animated! Hormones govern the menstrual and ovarian cycles. A GnRH from the hypothalamus stimulates the anterior pituitary to secrete FSH and LH. B FSH and LH stimulate a follicle to grow, an oocyte to mature, and the ovaries to secrete progesterone and estrogens that stimulate the endometrium to rebuild. C A midcycle LH surge triggers ovulation and the formation of a corpus luteum. D Progesterone and some estrogens released by the corpus luteum maintain the endometrium, but if no pregnancy occurs, they stop being released and the corpus luteum breaks down. ( Cengage Learning)
Match the terms and definitions.
As outlined in this chapter, sex can be defined at several levels: chromosomal, gonadal, and phenotypic. To this we can add psychological sex, the sex one believes themselves to be. Determining someones sex is a complex issue that is often difficult to resolve, as the case of Bruce Reimer (see Section 7.1) illustrates. In spite of the complexity surrounding this issue, the International Olympic Committee (IOC) and the International Association of Athletics Federations (IAFF) still use sex testing on female athletes to determine whether they can compete in athletic events as females. This has led to serious personal, social, and legal issues, and the practice has been widely condemned and widely defended. Lets examine two such cases here. An Indian athlete, Santhi Soundarajan, finished second in the 800-meter run at the Asian Games in Doha, Qatar, in 2006. After the race, she was asked to take a sex test. According to press reports, the tests showed that she appeared to have abnormal chromosomes. An official stated that she had more Y chromosomes than allowed. As a result, she was stripped of her medal, banned from further competition by the Indian Olympic Association, and shunned by her local community. Before the race in Doha, Santhi had competed in 8 international competitions and won 12 medals. Sometime after this incident, she attempted suicide. She now runs a training school for athletes in Tamil Nadu, India. Although the number and types of tests done on Santhi have not been revealed, such tests usually involve examination of the external genitals, a chromosome analysis, and measurement of hormone levels. Suppose you were on the committee deciding whether Santhi could compete as a female. Consider each of the following hypothetical tests one at a time and base your conclusions only on the results of that test. The results of a physical examination show she has female genitals. On this basis, would you allow her to keep her medal and compete as a female in future races? Suppose the results of a chromosomal analysis shows that she has an XY chromosome set and is chromosomally male. Would you allow her to keep her medal and compete as a female? Lastly, suppose a test for hormone levels shows that she has levels of the male sex hormone testosterone that are higher than average for females but at least 10 times lower than the average for males. Would you allow her to keep her medal and compete in future races as a female? Now, put the results of all three tests together, and consider them as a whole. What are your conclusions? Now, lets consider the case of a South African runner, Caster Semenya, who won the 800-meter run at the World Championships held in Berlin, Germany, in 2009. After the race, she was asked to undergo sex testing. The IAAF stated that the tests were requested to ascertain whether she had a rare medical condition that gave her an unfair physical advantage. The nature of the tests and their results were not released, but press reports indicate that she did not have ovaries or a uterus, and had testosterone levels intermediate between the averages for males and females. In the end, the IAAF agreed to keep the results of her tests confidential, and Caster was allowed to keep her medal and return to international competition in 2010. In both cases, what the IAAF considers the threshold for determining who can compete as a female has not been stated. Would you recommend that testing of female athletes be continued to ensure that males do not compete as females? Or should all such testing be banned?
As outlined in this chapter, sex can be defined at several levels: chromosomal, gonadal, and phenotypic. To this we can add psychological sex, the sex one believes themselves to be. Determining someones sex is a complex issue that is often difficult to resolve, as the case of Bruce Reimer (see Section 7.1) illustrates. In spite of the complexity surrounding this issue, the International Olympic Committee (IOC) and the International Association of Athletics Federations (IAFF) still use sex testing on female athletes to determine whether they can compete in athletic events as females. This has led to serious personal, social, and legal issues, and the practice has been widely condemned and widely defended. Lets examine two such cases here. An Indian athlete, Santhi Soundarajan, finished second in the 800-meter run at the Asian Games in Doha, Qatar, in 2006. After the race, she was asked to take a sex test. According to press reports, the tests showed that she appeared to have abnormal chromosomes. An official stated that she had more Y chromosomes than allowed. As a result, she was stripped of her medal, banned from further competition by the Indian Olympic Association, and shunned by her local community. Before the race in Doha, Santhi had competed in 8 international competitions and won 12 medals. Sometime after this incident, she attempted suicide. She now runs a training school for athletes in Tamil Nadu, India. Although the number and types of tests done on Santhi have not been revealed, such tests usually involve examination of the external genitals, a chromosome analysis, and measurement of hormone levels. Suppose you were on the committee deciding whether Santhi could compete as a female. Consider each of the following hypothetical tests one at a time and base your conclusions only on the results of that test. The results of a physical examination show she has female genitals. On this basis, would you allow her to keep her medal and compete as a female in future races? Suppose the results of a chromosomal analysis shows that she has an XY chromosome set and is chromosomally male. Would you allow her to keep her medal and compete as a female? Lastly, suppose a test for hormone levels shows that she has levels of the male sex hormone testosterone that are higher than average for females but at least 10 times lower than the average for males. Would you allow her to keep her medal and compete in future races as a female? Now, put the results of all three tests together, and consider them as a whole. What are your conclusions? Now, lets consider the case of a South African runner, Caster Semenya, who won the 800-meter run at the World Championships held in Berlin, Germany, in 2009. After the race, she was asked to undergo sex testing. The IAAF stated that the tests were requested to ascertain whether she had a rare medical condition that gave her an unfair physical advantage. The nature of the tests and their results were not released, but press reports indicate that she did not have ovaries or a uterus, and had testosterone levels intermediate between the averages for males and females. In the end, the IAAF agreed to keep the results of her tests confidential, and Caster was allowed to keep her medal and return to international competition in 2010. In both cases, what the IAAF considers the threshold for determining who can compete as a female has not been stated. Based on what is known about the test results in this case and the hypothetical tests in the first case, do you think the outcome in each case was fair?