Biological Science
Biological Science
5th Edition
ISBN: 9780321743671
Author: Scott Freeman
Publisher: PEARSON
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Chapter 4, Problem 5TYK
Summary Introduction

To review:

The functional groups that define the ends of a DNA (deoxyribonucleic acid) strand.

Introduction:

DNA is a double helical genetic material that is present in all the living cells. This molecule is self-replicating and replicates before the cell has to undergo cell division. Being the genetic material, DNA carries the necessary information to carry out all the functions of the cell. The structure of a DNA molecule was first given by Watson and Crick.

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A nucleotide is the monomeric building block of the polymer of DNA. To better understand the characteristics of DNA, it is important to understand how the monomers join to form the polymer. Use the following diagram of DNA (and the diagram of a nucleotide in the PowerPoint presentation) to label the listed features: 3' and 5' ends, nucleotide, phosphate group, sugar group, phosphodiester bond, nitrogenous base (pyrimidine and purine), and hydrogen bonds. NHZ NH2 HN OH₂N NH₂ 5. Looking at the polymer, why is a DNA considered antiparallel? 6. Why are the ends of DNA strands named 3' or 5'? 7. How do A:T interactions differ compared to G:C interactions? How does this affect stability of the bond pairs? 8. During gel electrophoresis, to which electrode (+ or -) does DNA migrate? Why?
One DNA chain of a DNA double helix contains 18% A, 35% T, 28% C, and 21% G. What is the composition of the complementary DNA chain?
A double-stranded DNA molecule is 1 cm long, and the percentage of adenine is 15%. How many cytosines does this DNA molecule contain?
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