Biological Science
Biological Science
5th Edition
ISBN: 9780321743671
Author: Scott Freeman
Publisher: PEARSON
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Chapter 4, Problem 4TYK

Which of the following rules apply to the synthesis of nucleic acids?

a. Nucleotides are added to the 5' end of nucleic acids.

b. The synthesis of nucleic acids cannot occur without the presence of an enzyme to catalyze the reaction.

c. Strands are synthesized in a parallel direction such that one end of the double-stranded product has the 3' ends and other has the 5' ends.

d. Complementary pairing between bases is required for copying nucleic acids.

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Ethidium Bromide is a chemical reagent that has been used to detect the presence of nucleic acids. It is known to fluoresce under UV light and the intensity of the fluoresence increases when it binds to the nucleic acids. Ethidium Bromide binds to polynucleotides  a   by binding directly to the bases on one of the strands. b   by intercalating itself between the base pair stacks. c   through the negatively charged phosphate groups. d   through the hydroxyl group of the sugar molecule.
Which of the following statements about nucleic acids is not correct? Select one: A. In DNA the distance between the strands of the double helix is relatively constant. B. The growing DNA polymer is synthesized in the 5' to 3' direction. C. The enzymes that catalyze DNA synthesis are known as DNA polymerases. D. RNA strands are synthesized in the 3' to 5' direction. E. Unlike DNA, RNA is easily cleaved because the 2'-OH group of the ribose is a nucleophile that catalyzes hydrolysis of the strand.
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