Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 3, Problem 26P
In humans, SRY is located near a pseudoautosomal region (PAR) of the Y chromosome, a region of homology between the X and Y chromosomes that allows them to synapse during meiosis in males and is a region of crossover between the chromosomes. The diagram below shows SRY in relation to the pseudoautosomal region.
About 1 in every 25,000 newborn infants is born with sex reversal; the infant is either an apparent male, but with two X chromosomes, or an apparent female, but with an X and a Y chromosome. Explain the origin of sex reversalin human males and females involving the SRY gene. (Hint: See Experimental Insight 3.1 for a clue about the mutational mechanism.)
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Butterflies have an X-Y sex-determination system that is different from that of flies or humans. Female butterflies may be either XY or X0, while butterflies with two or more X chromosomes are males. This photograph shows a tiger swallowtail gynandromorph, which is half male (left side) and half female (right side). Given that the first division of the zygote divides the embryo into the future right and left halves of the butterfly, propose a hypothesis that explains how nondisjunction during the first mitosis might have produced this unusual-looking butterfly.
Question is also in the picture.
Consider a cell with 2 pairs of homologous chromosomes where Chromosome 1 with genes VWXYZ is the homolog of Chromosome
2 with genes vwxyz while Chromosome 3 with genes PQRST is the homolog of Chromosome 4 with genes parst. If a reciprocal
translocation occurred between Chromosome 1 YZ genes and Chromosome 3 ST genes, give the following gamete types produced
after meiosis: (Answer in Arabic numbers only)
1. Gamete/s with non-recombinant chromosomes
2. Gamete/s with 1 recombinant chromosome
3. Gamete/s with 2 recombinant chromosomes
4. Gamete/s with gene duplications
5. Gamete/s with gene deletions
6. Gamete/s with 2 normal chromosome sequences
7. Gamete/s with 1 normal chromosome sequence
8. Gamete/s with balanced translocation
9. Gametes/ with all dominant genes
10. Gamete/s with all recessive genes
11. Gamete/s with 10 different genes
12. Gamete/s with TSXWV genes
13. Gamete/s with vwxyz genes
14. Gamete/s with pqrst genes
15.Gamete/s with PORYZ
Kuliev and Verlinsky (2004) state that there was a relatively high number of separation errors at meiosis I. In these cases the centromere underwent a premature division, occurring at meiosis I rather than meiosis II. Regarding chromosome 21, what would you expect to be the chromosome 21 complement in the secondary oocyte in which you saw a single chromatid (monad) for chromosome 21 in the first polar body? If this secondary oocyte was involved in fertilization, what would be the expected consequences?
Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 3 - Examine the following diagrams of cells from an...Ch. 3 - Our closest primate relative, the chimpanzee, has...Ch. 3 -
3. In a test of his chromosome theory of...Ch. 3 - Cohesion between sister chromatids, as well as...Ch. 3 - 5. The diploid number of the hypothetical animal...Ch. 3 - 6. An organism has alleles R1 and R2 on one pair...Ch. 3 - Explain how the behavior of homologous chromosomes...Ch. 3 - 8. Suppose crossover occurs between the homologous...Ch. 3 -
9. Alleles A and a are on one pair of autosomes,...Ch. 3 - Prob. 10P
Ch. 3 - Describe the role of the following structures or...Ch. 3 - A womans father has ornithine transcarbamylase...Ch. 3 - In humans, hemophilia A (OMIM 306700) is an...Ch. 3 -
14. A wild-type male and a wild-type female...Ch. 3 - 15. A woman with severe discoloration of her tooth...Ch. 3 - 16. In a large metropolitan hospital, cells from...Ch. 3 - In cats, tortoiseshell coat color appears in...Ch. 3 - 18. The gene causing Coffin–Lowry syndrome (OMIM...Ch. 3 - 19. Four eye-color mutants in Drosophila—apricot,...Ch. 3 - 20. For each pedigree shown,
a. Identify which...Ch. 3 - 21. Use the blank pedigrees provided to depict...Ch. 3 - 22. Figure 3.22 (page 89) illustrates reciprocal...Ch. 3 - 23. In fruit flies, yellow body (y) is recessive...Ch. 3 - 24. In a species of fish, a black spot on the...Ch. 3 - LeschNyhan syndrome (OMIM 300322) is a rare...Ch. 3 - 26. In humans, SRY is located near a...Ch. 3 - 27. In an 1889 book titled Natural Inheritance...Ch. 3 - 30. Drosophila has a diploid chromosome number of...Ch. 3 - 29. A wild-type Drosophila male and female are...Ch. 3 - 28. In Drosophila, the X-linked echinus eye...Ch. 3 - 31. While examining a young tortoiseshell cat, you...Ch. 3 - 32. Redgreen color blindness in humans is...
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