Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 3, Problem 8P
Suppose crossover occurs between the homologous chromosomes in the previous problem. At what stage of M phase do alleles D and d segregate?
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Suppose crossover occurs between the homologous chromosomes in the previous problem. At what stage of M phase
do alleles D and d segregate?
Suppose you have a line of mice that has cytologicallydistinct forms of chromosome 4. The tip of the chromosome can have a knob (called 4K) or a satellite (4S) orneither (4). Here are sketches of the three types:4K4S4You cross a 4K/4S female with a 4/4 male and find thatmost of the progeny are 4K/4 or 4S/4, as expected.However, you occasionally find some rare types asfollows (all other chromosomes are normal):a. 4K/4K/4b. 4K/4S/4c. 4KExplain the rare types that you have found. Give, asprecisely as possible, the stages at which they originate,and state whether they originate in the male parent,the female parent, or the zygote. (Give brief reasons.)
In the haploid yeast Saccharomyces cerevisiae, the twomating types are known as MATa and MATα. You cross apurple (ad-) strain of mating type a and a white (ad+)strain of mating type α. If ad- and ad+ are alleles of onegene, and a and α are alleles of an independently inherited gene on a separate chromosome pair, what progenydo you expect to obtain? In what proportions?
Chapter 3 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 3 - Examine the following diagrams of cells from an...Ch. 3 - Our closest primate relative, the chimpanzee, has...Ch. 3 -
3. In a test of his chromosome theory of...Ch. 3 - Cohesion between sister chromatids, as well as...Ch. 3 - 5. The diploid number of the hypothetical animal...Ch. 3 - 6. An organism has alleles R1 and R2 on one pair...Ch. 3 - Explain how the behavior of homologous chromosomes...Ch. 3 - 8. Suppose crossover occurs between the homologous...Ch. 3 -
9. Alleles A and a are on one pair of autosomes,...Ch. 3 - Prob. 10P
Ch. 3 - Describe the role of the following structures or...Ch. 3 - A womans father has ornithine transcarbamylase...Ch. 3 - In humans, hemophilia A (OMIM 306700) is an...Ch. 3 -
14. A wild-type male and a wild-type female...Ch. 3 - 15. A woman with severe discoloration of her tooth...Ch. 3 - 16. In a large metropolitan hospital, cells from...Ch. 3 - In cats, tortoiseshell coat color appears in...Ch. 3 - 18. The gene causing Coffin–Lowry syndrome (OMIM...Ch. 3 - 19. Four eye-color mutants in Drosophila—apricot,...Ch. 3 - 20. For each pedigree shown,
a. Identify which...Ch. 3 - 21. Use the blank pedigrees provided to depict...Ch. 3 - 22. Figure 3.22 (page 89) illustrates reciprocal...Ch. 3 - 23. In fruit flies, yellow body (y) is recessive...Ch. 3 - 24. In a species of fish, a black spot on the...Ch. 3 - LeschNyhan syndrome (OMIM 300322) is a rare...Ch. 3 - 26. In humans, SRY is located near a...Ch. 3 - 27. In an 1889 book titled Natural Inheritance...Ch. 3 - 30. Drosophila has a diploid chromosome number of...Ch. 3 - 29. A wild-type Drosophila male and female are...Ch. 3 - 28. In Drosophila, the X-linked echinus eye...Ch. 3 - 31. While examining a young tortoiseshell cat, you...Ch. 3 - 32. Redgreen color blindness in humans is...
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- An individual is heterozygous for a reciprocal translocation, with the following chromosomes: A • B C D E F A • B C V W X R ST • U D E F R ST • U V W X Q. Draw a picture of these chromosomes pairing in prophase I of meiosis.arrow_forwardConsider three pairs of homologous chromosomes with centromere labeled A/a, B/B, C/c. How many kinds of meiotic products can this individual produce?arrow_forwardDeduce the phenotypic proportions in the progeny of thefollowing crosses of autotetraploids in which the a+/a locus is very close to the centromere. (Assume that the fourhomologous chromosomes of any one type pair randomly two by two and that only one copy of the a+ allele isnecessary for the wild-type phenotype.)a. a+/a+/a/a × a/a/a /ab. a+/a/a /a × a/a/a/ac. a+/a/a /a × a+/a/a /ad. a+/a+/a /a × a+/a/a /aarrow_forward
- An individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B ● C D E F G, A B • C D V W X, R S •T U E F G, R S•T U V W Xa. Draw the pairing arrangement of these chromosomes in prophase 1 of meiosis. Mention their gametic composition. b. Draw the alternate, adjacent I, and adjacent II segregation patterns in anaphase I of meiosis. Mention their gametic composition.arrow_forwardLet’s say there is an organism with two pairs of alleles, W/w and Z/z, each pair is located on a different pair of chromosomes in the organism’s somatic cells. During Prophase, what will you observe in the somatic cells?arrow_forwardA reciprocal translocation between chromosome 1 and 2 in Drosophila resulted in AB//CPQR and MN//ODEF. Double stroke indicates centromere location. (i) Diagram the alignment of these chromosomes during meiosis. (ii) What will be the gametes produced by alternate segregation, adjacent 1 segregation and adjacent 2 segregation?arrow_forward
- Let’s say there is an organism with two pairs of alleles, W/w and Z/z, each pair is located on a different pair of chromosomes in the organism’s somatic cells. During Metaphase, what will you observe in the somatic cells?arrow_forwardIf the G locus were 50 or more map units from the centromere, what types and proportions of gametes would the F1 be expected to produce? Derive the expected F2 genotypic and phenotypicarrow_forwardThe incidence of Down syndrome will be high (nearly 50%) among the offspring of a parent with Down syndrome. Diagram meiosis in the Down syndrome parent to explain why progeny have such a high risk for chromosome 21 aneuploidy. Explain in addition why the incidence of Down syndrome among these children might be less than 50%.arrow_forward
- Let’s say there is an organism with two pairs of alleles, W/w and Z/z, each pair is located on a different pair of chromosomes in the organism’s somatic cells. During G2, what will you observe in the somatic cells?arrow_forward11:52 In the fruit fly, vestigial wings and hairy body are produced by two recessive genes located on different chromosomes. The normal alleles, long wings and hairless body, are dominant. Suppose a vestigial-winged hairy male is crossed with a homozygous normal female. What types of progeny would be expected? If the F1 generation from this cross are permitted to mate randomly among themselves, what progeny would be expected in the F2? Show complete genotypes, phenotypes and ratios for each generation. 7. Other problems: How do you know the genotype of organisms with a dominant phenotype? Is it homozygous or heterozygous? A pea plant exhibits a purple color, but you are unsure of its genotype. With what could you cross this plant to determine its genotype? Show all of 8. your work for the cross. What is this type of cross called? Incomplete dominance: Genes code for the production of specific proteins, many of which are enzymes. Different alleles at a locus code for alternative forms…arrow_forwardAn individual heterozygous for a reciprocal translocation possesses the following chromosomes: A B • C D E F G A B • C D V W X R S • T U E F G R S • T U V W X Q. Draw the pairing arrangement of these chromosomes in prophase I of meiosis.arrow_forward
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