Biochemistry
Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
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Chapter 28, Problem 11P
Interpretation Introduction

Interpretation:

The change in the helical twist of the DNA, Δϕ as compared to the value in B-DNA should be calculated.

Concept introduction:

The spiral structure of deoxyribonucleic acid may be a low energy type that makes its formation thermodynamically favorable. If you image 2 deoxyribonucleic acid strands joined by gas bonds however in a very non-helical, straight type, you'll be able to merely twist the strands concerning their central axis to create a spiral structure.

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1 of 1 Q3. An H-DNA region has one all purine (blue) and one all pyrimidine (brown) strand, allowing it to form a triple- stranded helix by doubling back. Draw the detailed chemical structures for all the base- pairing (Watson-Click paring + Hoogsteen paring) in the triple helix shown in the figure. 5' Pyr-GTAGGAGCGG- 3 Pur-CATCCTGGCC 5 3 Pur Pyr
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