Chapter 27, Problem 52E

Interpretation Introduction

Interpretation:

A method to synthesize $\left(R\right)\text{-butan-2-amine}$ from $\left(S\right)\text{-butan-2-ol}$ should be determined.

Concept introduction:

Nucleophilic substitution reaction $\left({\text{S}}_{\text{N}}2\right)$ is a single step substitution reaction in which electron rich species substitute leaving group. The attack takes place from the back side of the electrophilic center thus an inversion of the configuration takes place. Also, there is a single transition state because bond breaking and bond making occurs simultaneously.