Concept explainers
Interpretation:
The approach of private corporation Celera to the sequencing of the human genome and the advantage of this approach should be explained briefly.
Concept introduction:
A genome is the complete set of DNA of an organic species including all genes.
The mapping of human genome is led by two organizations. They are the Human Genome Project and Celera Genomics.
In Celera which is a subsidiary of Quest diagnosis, the complete DNA is fragmented into unidentified particles and using techniques that are driven by supercomputer and instruments a new DNA sequence is established.
Genome Sequencing: Genome Sequencing is figuring out the complete DNA of an organism at once. Using this the order of
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Fundamentals of General, Organic, and Biological Chemistry (8th Edition)
- Why was sequencing the human genome such a formidable task?arrow_forwarda) What are vectors? Describe extensively the roles vectors play in genetic engineering? Write short notees on the following: Recombinant DNA, Cloning b) What are restriction enzymes? Describe extensively the roles restriction enzymes play in genetic engineering? Write short notees on the following: Selectable markers, Cloningarrow_forwardWhat is exome sequencing used for?arrow_forward
- You are performing an experiment using CRISPR-cas9 to genetically modify the LacZ gene of a culture of E. coli. After you run the experiment, you decide to use gel electrophoresis to genotype the different bacterial cultures to determine if the gene editing was successful. How could your electrophoresis results confirm that the PCR was successful? And how could your electrophoresis results confirm that you successfully extracted genomic DNA from your bacterial samples?arrow_forwardWhat is recombinant DNA technology ?arrow_forwardThere are four possible observations that suggest an error occurred in a PCR reaction: a) Sequence errors in the amplicon, b) the amplicon is the wrong size, c) there is no 6. Application: e are four possible observations that suggest an error occurred in a PCR reaction: 7 Sequence errors in the amplicon, b) the amplicon is the wrong size, c) there is ho amplicon, or d) there are multiple, non-specific amplicons. At tô thể possible cause, write which error is most likely associated with the cause (the first one is done as an example): Cause Would result in the following error Unbalanced nucleotide concentrations a) Sequence errors in the amplicon Annealing temperature too low Poor primer specificity (wrong sequence) Template DNA degraded Contamination of reaction tubes or solutions Lack of Mg2+ in reaction mixture Pick one cause and result pair and discuss in detail on the next page why one would lead to the other:arrow_forward
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- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage Learning