(a)
Interpretation: The amine formed by reduction of given amide is to be determined.
Concept introduction: The synthesis of amine can be carried out by reduction of nitro compounds, nitriles and amides. Nitro compounds can be reduced to
(b)
Interpretation: The amine formed by reduction of given amide is to be determined.
Concept introduction: The synthesis of amine can be carried out by reduction of nitro compounds, nitriles and amides. Nitro compounds can be reduced to amines using catalytic hydrogenation or iron/palladium metal in presence of acid. Nitriles and amides are reduced to amines using lithium aluminium hydride.
(c)
Interpretation: The amine formed by reduction of given amide is to be determined.
Concept introduction: The synthesis of amine can be carried out by reduction of nitro compounds, nitriles and amides. Nitro compounds can be reduced to amines using catalytic hydrogenation or iron/palladium metal in presence of acid. Nitriles and amides are reduced to amines using lithium aluminium hydride.
Want to see the full answer?
Check out a sample textbook solutionChapter 25 Solutions
Organic Chemistry
- 3.63 Quinapril (trade name Accupril) is a drug used to treat hypertension and congestive heart falure. a. Identify the functional groups in quinapril. b. Classify any alcohol, amide, or amine as 1°, 2°, or 3°º. H. C. At which sites can quinapril hydrogen bond to water? d. At which sites can quinapril hydrogen bond to acetone [(CH3),CO]? e. Label the most acidic hydrogen atom. f. Which site is most basic? quinaprilarrow_forwardWhat amine is formed by reduction of each amide?arrow_forwardThe hydrolysis of an amide in acidic conditions forms A. a carboxylate salt and an alcohol B. a carboxylate salt and an amine C. an alcohol and an amine salt (an ammonium ion) D. a carboxylic acid and an amine salt (an ammonium ion)arrow_forward
- What amide(s) can be used to prepare each amine by reduction?arrow_forwardWhat amides will form each amine on treatment with LiAlH4?arrow_forwardExplin how you would separate a mixture containing benzoic acid and a neutral substance, benzophenone. Both compounds are insoluble in water and soluble in ether.arrow_forward
- Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage LearningOrganic And Biological ChemistryChemistryISBN:9781305081079Author:STOKER, H. Stephen (howard Stephen)Publisher:Cengage Learning,General, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage Learning