Concept explainers
(a)
Interpretation:
Whether the citrate shuttle system is used in (1) the β-oxidation pathway, (2) ketogenesis, or (3) lipogenesis has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is an acyclic process to synthesize saturated fatty acid.
The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acetyl CoA is degraded to acetyl CoA. This pathway is termed as β-oxidation pathway.
Ketogenesis is a
(b)
Interpretation:
Whether acetyl ACP is used in (1) the β-oxidation pathway, (2) ketogenesis, or (3) lipogenesis has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is an acyclic process to synthesize saturated fatty acid.
The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acetyl CoA is degraded to acetyl CoA. This pathway is termed as β-oxidation pathway.
Ketogenesis is a metabolic process by which ketone bodies are produced by the breakdown of fatty acids and ketogenic amino acids. This metabolic process supplies organs with needed energy under certain circumstances such as starvation. Fatty acid molecules degrade into acetyl CoA which are utilized as reactants in the process of ketogenesis. acetyl CoA undergo the process of condensation twice, followed by chain cleavage and hydrogenation to produce ketone bodies.
(c)
Interpretation:
Whether H2O is used in (1) the β-oxidation pathway, (2) ketogenesis, or (3) lipogenesis has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is an acyclic process to synthesize saturated fatty acid.
The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acetyl CoA is degraded to acetyl CoA. This pathway is termed as β-oxidation pathway.
Ketogenesis is a metabolic process by which ketone bodies are produced by the breakdown of fatty acids and ketogenic amino acids. This metabolic process supplies organs with needed energy under certain circumstances such as starvation. Fatty acid molecules degrade into acetyl CoA which are utilized as reactants in the process of ketogenesis. acetyl CoA undergo the process of condensation twice, followed by chain cleavage and hydrogenation to produce ketone bodies.
(d)
Interpretation:
Whether H2O is used as a reactant in (1) the β-oxidation pathway, (2) ketogenesis, or (3) lipogenesis has to be determined.
Concept introduction:
Lipogenesis is the process employed for the synthesis of fatty acid. The starting precursor for the synthesis is acetyl CoA. The enzyme employed for the process is fatty acid synthase. It is a multienzyme complex that ties the reaction responsible for the synthesis of fatty acid. The fatty acid is synthesized in two parts. In the first part, there is citrate-malate shuttle system and in the second part, there is an acyclic process to synthesize saturated fatty acid.
The fatty acids are broken down to provide energy. The breakdown of fatty acids is a three parts process. In the first part, the fatty acid is activated. In the second part, the transportation of fatty acid into the mitochondrial matrix is facilitated by a shuttle mechanism. In the third part, the fatty acid is readily oxidized, cycling through a series of four reactions. In these series of reactions, acetyl CoA is degraded to acetyl CoA. This pathway is termed as β-oxidation pathway.
Ketogenesis is a metabolic process by which ketone bodies are produced by the breakdown of fatty acids and ketogenic amino acids. This metabolic process supplies organs with needed energy under certain circumstances such as starvation. Fatty acid molecules degrade into acetyl CoA which are utilized as reactants in the process of ketogenesis. acetyl CoA undergo the process of condensation twice, followed by chain cleavage and hydrogenation to produce ketone bodies.
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Chapter 25 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- true or false The equilibrium constant for this reaction is 0.20. N2O4(g) ⇔ 2NO2(g) Based on the above, the equilibrium constant for the following reaction is 5. 4NO2(g) ⇔ 2N2O4(g)arrow_forwardtrue or false The equilibrium constant for this reaction is 0.20. N2O4(g) ⇔ 2NO2(g) Based on the above, the equilibrium constant for the following reaction is 0.4. 2N2O4(g) ⇔ 4NO2(g)arrow_forwardtrue or false Using the following equilibrium, if heat is added the equilibrium will shift toward the reactants. N2(g) + 3H2(g) ⇔ 2NH3(g) + heatarrow_forward
- True or False Using the following equilibrium, if heat is added the equilibrium will shift toward the products. N2O4(g) + heat ⇔ 2NO2(g)arrow_forwardtrue or false Using the following equilibrium, if solid carbon is added the equilibrium will shift toward the products. C(s) + CO2(g) ⇔ 2CO(g)arrow_forwardProvide the complete mechanism for the reaction below. You must include appropriate arrows,intermediates, and formal charges. Please also provide a reason to explain why the 1,4-adduct is preferred over the 1,3-adduct.arrow_forward
- Which of the following pairs are resonance structures of one another? I. III. || III IV + II. :0: n P !༠ IV. EN: Narrow_forwardPredict the major organic product(s) and byproducts (either organic or inorganic) for thefollowing reactions.arrow_forwardA 8.25 g sample of aluminum at 55°C released 2500 J of heat. The specific heat of aluminum is 0.900 J/g°C. The density of aluminum is 2.70 g/mL. Calculate the final temperature of the aluminum sample in °C.arrow_forward
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage LearningChemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage LearningGeneral, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage Learning
- Organic And Biological ChemistryChemistryISBN:9781305081079Author:STOKER, H. Stephen (howard Stephen)Publisher:Cengage Learning,
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