Concept explainers
(a)
Interpretation:
Whether the compound ketoacyl CoA is associated with (1) the β-oxidation pathway, (2) ketogenesis, or (3) both the β-oxidation pathway and ketogenesis has to be identified.
Concept introduction:
Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules.
The β-oxidation is a catabolic process occurring in the body through which, fatty acid molecules are broken down in the mitochondria of the cells to generate energy. The process involves breaking down long fatty acid chains that have been converted to acetyl CoA chains into smaller fatty acetyl CoA chains. The fatty acid chain is broken down until the final acetyl CoA chain cannot be broken down any further. The end products of this
(b)
Interpretation:
Whether the compound acetoacetyl CoA is associated with (1) the β-oxidation pathway, (2) ketogenesis, or (3) both the β-oxidation pathway and ketogenesis has to be identified.
Concept introduction:
Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
β-oxidation is a catabolic process occurring in the body through which, fatty acid molecules are broken down in the mitochondria of the cells to generate energy. The process involves breaking down long fatty acid chains that have been converted to acetyl CoA chains into smaller fatty acetyl CoA chains. The fatty acid chain is broken down until the final acetyl CoA chain cannot be broken down any further. The end products of this metabolic process are acetyl CoA, FADH2 and NADH. These three molecules later enter the Krebs cycle where they are used to produce ATP molecules.
(c)
Interpretation:
Whether the compound acetoacetate is associated with (1) the β-oxidation pathway, (2) ketogenesis, or (3) both the β-oxidation pathway and ketogenesis has to be identified.
Concept introduction:
Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
β-oxidation is a catabolic process occurring in the body through which, fatty acid molecules are broken down in the mitochondria of the cells to generate energy. The process involves breaking down long fatty acid chains that have been converted to acetyl CoA chains into smaller fatty acetyl CoA chains. The fatty acid chain is broken down until the final acetyl CoA chain cannot be broken down any further. The end products of this metabolic process are acetyl CoA, FADH2 and NADH. These three molecules later enter the Krebs cycle where they are used to produce ATP molecules.
(d)
Interpretation:
Whether the compound hydroxyacyl CoA is associated with (1) the β-oxidation pathway, (2) ketogenesis, or (3) both the β-oxidation pathway and ketogenesis has to be identified.
Concept introduction:
Ketogenesis occurs in the mitochondria of the liver cells. The initial reactants are the molecules of acetyl CoA which are produced by the β-oxidation of fatty acid molecules. Ketone bodies are generally produced when the amount of acetyl CoA in the body is much larger than the amount of oxaloacetate. This happens due to the carbohydrate-lipid imbalance in the body caused by much smaller intake of food rich in carbohydrates, or inefficient processing of glucose by the body.
β-oxidation is a catabolic process occurring in the body through which, fatty acid molecules are broken down in the mitochondria of the cells to generate energy. The process involves breaking down long fatty acid chains that have been converted to acyl CoA chains into smaller fatty acyl CoA chains. The fatty acid chain is broken down until the final acyl CoA chain cannot be broken down any further. The end products of this metabolic process are acetyl CoA, FADH2 and NADH. These three molecules later enter the Krebs cycle where they are used to produce ATP molecules.
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Chapter 25 Solutions
EBK GENERAL, ORGANIC, AND BIOLOGICAL CH
- 5. Drawn the structure of the compound (molecular formula C12H16) with the longest λmax in its UV-vis spectrum.arrow_forwardUse solubility rules to complete balance molecular equations, and provide total and net ionic equations.arrow_forwardUse solubility rules to provide balance molecular equation, total, and net ionic equationarrow_forward
- Use solubility rules to provide balance molecular equation, total, and net ionic equationarrow_forwardBr HO ? HO ✓ OHarrow_forwardUse the literature Ka value of the acetic acid, and the data below to answer these questions. Note: You will not use the experimental titration graphs to answer the questions that follow. Group #1: Buffer pH = 4.35 Group #2: Buffer pH = 4.70 Group #3: Buffer pH = 5.00 Group #4: Buffer pH = 5.30 Use the Henderson-Hasselbalch equation, the buffer pH provided and the literature pKa value of acetic acid to perform the following: a) calculate the ratios of [acetate]/[acetic acid] for each of the 4 groups buffer solutions above. b) using the calculated ratios, which group solution will provide the best optimal buffer (Hint: what [acetate]/[acetic acid] ratio value is expected for an optimal buffer?) c) explain your choicearrow_forward
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- General, Organic, and Biological ChemistryChemistryISBN:9781285853918Author:H. Stephen StokerPublisher:Cengage LearningOrganic And Biological ChemistryChemistryISBN:9781305081079Author:STOKER, H. Stephen (howard Stephen)Publisher:Cengage Learning,Chemistry for Today: General, Organic, and Bioche...ChemistryISBN:9781305960060Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. HansenPublisher:Cengage Learning
- Introduction to General, Organic and BiochemistryChemistryISBN:9781285869759Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar TorresPublisher:Cengage Learning
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