The systematic name for the given steroid is to be determined. Concept introduction: Steroids are a group of compounds that are obtained from lipids of plants and animals. Chemically, they are the derivatives of perhydrocyclopentanophenanthrene ring system. Pregnane is a 21-carbon saturated hydrocarbon steroid that is responsible for producing progestins. It is an alkane -based steroid, but group of 5 − α or β − pregnan-ol are alcohol-based steroids. Androstan are a group of steroid hormones. The 5 α − Estran − one group of steroids include hormones, such as androgen, estrogen, and progesterone. The numbering of the carbon atoms and naming of the ring system are done as shown in the figure. The A, B ring junction may be cis or trans , but B, C and C, D ring junctions are mostly trans . The methyl groups attached at the points of the ring junction are called angular methyl groups and they are the reference points for the stereochemical designations. Conventionally, groups that lie on the top of the molecule, same as that of the angular methyl group, are designated as β − groups while those at the bottom are designated as α − groups . When α and β positions are applied for hydrogen atom at C-5, and the A, B ring junction is cis , it is designated as 5 β − series and when the A, B ring junction is trans , it is designated as 5 α − series . The nature of the R − group(s) at the carbon-position determines the base name of the individual steroid.

Question

Want to see the full answer?

Answer 1

Question

Chapter 23, Problem 7Q

Interpretation Introduction

Interpretation:

The systematic name for the given steroid is to be determined.

Concept introduction:

Steroids are a group of compounds that are obtained from lipids of plants and animals. Chemically, they are the derivatives of perhydrocyclopentanophenanthrene ring system.

Pregnane is a 21-carbon saturated hydrocarbon steroid that is responsible for producing progestins. It is an alkane-based steroid, but group of 5−α or β− pregnan-ol are alcohol-based steroids.

Androstan are a group of steroid hormones. The 5α−Estran−one group of steroids include hormones, such as androgen, estrogen, and progesterone.

The numbering of the carbon atoms and naming of the ring system are done as shown in the figure. The A, B ring junction may be cis or trans, but B, C and C, D ring junctions are mostly trans.

The methyl groups attached at the points of the ring junction are called angular methyl groups and they are the reference points for the stereochemical designations.

Conventionally, groups that lie on the top of the molecule, same as that of the angular methyl group, are designated as β−groups while those at the bottom are designated as α−groups. When α and β positions are applied for hydrogen atom at C-5, and the A, B ring junction is cis, it is designated as 5β−series and when the A, B ring junction is trans, it is designated as 5α−series.

The nature of the R−group(s) at the carbon-position determines the base name of the individual steroid.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

An orange laser has a wavelength of 610 nm. What is the energy of this light?

The molar absorptivity of a protein in water at 280 nm can be estimated within ~5-10% from its content of the amino acids tyrosine and tryptophan and from the number of disulfide linkages (R-S-S-R) between cysteine residues: Ε280 nm (M-1 cm-1) ≈ 5500 nTrp + 1490 nTyr + 125 nS-S where nTrp is the number of tryptophans, nTyr is the number of tyrosines, and nS-S is the number of disulfide linkages. The protein human serum transferrin has 678 amino acids including 8 tryptophans, 26 tyrosines, and 19 disulfide linkages. The molecular mass of the most dominant for is 79550. Predict the molar absorptivity of transferrin. Predict the absorbance of a solution that’s 1.000 g/L transferrin in a 1.000-cm-pathlength cuvet. Estimate the g/L of a transferrin solution with an absorbance of 1.50 at 280 nm.

In GC, what order will the following molecules elute from the column? CH3OCH3, CH3CH2OH, C3H8, C4H10