Chapter 23, Problem 7PP

Interpretation Introduction

Interpretation:

The three-dimensional formula for androsterone and norethynodrel is to be given.

Concept Introduction:

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Androsterone, a secondary male sex hormone, is an endogenous steroid hormone. It is a weak androgen with a molecular formula of ${\text{C}}_{\text{19}}{\text{H}}_{\text{30}}{\text{O}}_{\text{2}}$.

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The structure of androsterone consists of four rings, three six membered carbon rings and one five membered carbon ring. It consists of a hydroxyl group at the third carbon atom, two methyl groups at the tenth and the thirteenth carbon positions respectively, and a ketone group at the seventeenth carbon position.

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Norethynodrel is a group of synthetic steroids having functions similar to those of progesterone. These are widely used as oral contraceptives; however, now have been discontinued. Its molecular formula is ${\text{C}}_{\text{20}}{\text{H}}_{\text{26}}{\text{O}}_{\text{2}}$.

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The structure of norethynodrel consists of three six membered carbon ring and one five membered carbon ring. It consists of a hydroxyl group at the third carbon atom, two methyl groups at the tenth and the thirteenth carbon positions respectively, and a ketone group at the seventeenth carbon position.