Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

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Chapter 22, Problem 4MCQ

Summary Introduction

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Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

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Kinetics: One-Compartment First-Order Absorption 1. In vivo testing provides valuable insight into a drug’s kinetics. Assessing drug kinetics following multiple routes of administration provides greater insight than a single route of administration alone. The following data was collected in 250-g rats following bolus IV, oral (PO), and intraperitoneal (ip) administration. Using this data and set of graphs, determine:(calculate for each variable) (a) k, C0, V, and AUC* for the bolus iv data (b) k, ka, B1, and AUC* for the po data c) k, ka, B1, and AUC* for the ip data (d) relative bioavailability for po vs ip, Fpo/Fip (e)absolute ip bioavailability, Fip (f) absolute po bioavailability, Fpo

3. A promising new drug is being evaluated in human trials. Based on preliminary human tests, this drug is most effective when plasma levels exceed 30 mg/L. Measurements from preliminary tests indicate the following human pharmacokinetic parameter values: t1/2,elim = 4.6hr, t1/2,abs = 0.34hr, VD = 0.29 L/kg, Foral = 72%. Based on these parameters, estimate the following if a 49 kg woman were to receive a 1000mg oral dose of this drug: (a) Estimate the plasma concentration of the drug at 1hr, 6 hr, and 20hr after taking the drug ( Concentration estimate) (b) Estimate the time for maximum plasma concentration (tmax). (c) Estimate the maximum plasma concentration (Cmax). (d) Estimate the time at which the plasma level first rises above 30 mg/L. (Note this is a trial and error problem where you must guess a time, plug it into the concentration equation, and determine if it is close to 30 mg/L. Hint: based on part (a) it should be apparent that the answer is less than 1hr.) (e)…

Answer 2

Question

Chapter 22, Problem 4MCQ

Summary Introduction

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

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Answer 3

Question

Chapter 22, Problem 4MCQ

Summary Introduction

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

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Answer 4

Question

Chapter 22, Problem 4MCQ

Summary Introduction

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

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Answer 5

Chapter 22, Problem 4MCQ

Summary Introduction

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

Answer 6

Chapter 22, Problem 4MCQ

Summary Introduction

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

Answer 7

Chapter 22, Problem 4MCQ

Summary Introduction

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

Answer 8

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Ch. 22.1 - Prob. 1AYP Ch. 22.1 - Prob. 2AYP Ch. 22.2 - Prob. 3AYP Ch. 22.2 - Prob. 4AYP Ch. 22.3 - Prob. 2CF Ch. 22.3 - List the possible causative agents for the...Ch. 22.3 - Prob. 6AYP Ch. 22.3 - Name one distinct feature for each of the acute...Ch. 22.3 - Prob. 8AYP Ch. 22.3 - Prob. 9AYP

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

Solution Summary: The author explains that the paramyxoviridae group of viruses is a large family of single-stranded, enveloped RNA viruses that cause mumps and measles.

Concept explainers

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

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Chapter 22 Solutions

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

Solution Summary: The author explains that the paramyxoviridae group of viruses is a large family of single-stranded, enveloped RNA viruses that cause mumps and measles.

Concept explainers

Introduction: Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.

Want to see the full answer?

Chapter 22 Solutions

Introduction:

Viruses are biological agents that contain either DNA or RNA as their genetic material. They are composed of nucleic acids and proteins. They exist as a non-living particle when present outside their host but able to multiply inside living host.