ACHIEVE:INTRO TO GENETIC ANALYSIS 1TERM
12th Edition
ISBN: 9781319401399
Author: Griffiths
Publisher: MAC HIGHER
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Chapter 2, Problem 75P
A.
Summary Introduction
To determine: The mode of inheritance best accounts for the transmission of the specified trait.
Introduction: Amelogenesis imperfecta is a congenital disease that exhibits among a rare, unusual development of the enamel or outer covering of the crown of teeth and independent to several systemic or generalized situations.
B.
Summary Introduction
To determine: The genotypes of all family members according to hypothesis.
Introduction: Amelogenesis imperfecta is the title granted to a heterogeneous group of situations identified by acquired developmental enamel defects.
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This pedigree traces the inheritance of a rare disease in humans.
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The condition phenylketonuria is caused by a recessive allele. There are two carriers who have progeny.a. Give the gene notation. b. Give the expected genotypic and phenotypic ratios. c. What is the probability that their child will be heterozygous if they have a normal child?d. What is the probability of having two affected children and one normal child if they have three children?
Chapter 2 Solutions
ACHIEVE:INTRO TO GENETIC ANALYSIS 1TERM
Ch. 2 - Prob. 1PCh. 2 - Prob. 2PCh. 2 - Prob. 3PCh. 2 - Prob. 4PCh. 2 - Prob. 5PCh. 2 - Prob. 6PCh. 2 - Prob. 7PCh. 2 - Prob. 8PCh. 2 - Prob. 9PCh. 2 - Prob. 10P
Ch. 2 - Prob. 11PCh. 2 - Prob. 12PCh. 2 - Prob. 13PCh. 2 - Prob. 14PCh. 2 - Prob. 15PCh. 2 - Prob. 17PCh. 2 - Prob. 18PCh. 2 - Prob. 19PCh. 2 - Prob. 20PCh. 2 - Prob. 21PCh. 2 - Prob. 22PCh. 2 - Prob. 23PCh. 2 - Prob. 24PCh. 2 - Prob. 25PCh. 2 - Prob. 26PCh. 2 - Prob. 27PCh. 2 - Prob. 28PCh. 2 - Prob. 29PCh. 2 - Prob. 30PCh. 2 - Prob. 31PCh. 2 - Prob. 32PCh. 2 - Prob. 33PCh. 2 - Prob. 34PCh. 2 - Prob. 35PCh. 2 - Prob. 36PCh. 2 - Prob. 37PCh. 2 - Prob. 38PCh. 2 - Prob. 39PCh. 2 - Prob. 40PCh. 2 - Prob. 41PCh. 2 - Prob. 42PCh. 2 - Prob. 43PCh. 2 - Prob. 44PCh. 2 - Prob. 45PCh. 2 - Prob. 46PCh. 2 - Prob. 47PCh. 2 - Prob. 48PCh. 2 - Prob. 49PCh. 2 - Prob. 50PCh. 2 - Prob. 51PCh. 2 - Prob. 52PCh. 2 - Prob. 53PCh. 2 - Prob. 54PCh. 2 - Prob. 55PCh. 2 - Prob. 56PCh. 2 - Prob. 56.1PCh. 2 - Prob. 56.2PCh. 2 - Prob. 56.3PCh. 2 - Prob. 56.4PCh. 2 - Prob. 56.5PCh. 2 - Prob. 56.6PCh. 2 - Prob. 56.7PCh. 2 - Prob. 56.8PCh. 2 - Prob. 56.9PCh. 2 - Prob. 56.10PCh. 2 - Prob. 56.11PCh. 2 - Prob. 56.12PCh. 2 - Prob. 56.13PCh. 2 - Prob. 56.14PCh. 2 - Prob. 56.15PCh. 2 - Prob. 57PCh. 2 - Prob. 58PCh. 2 - Prob. 59PCh. 2 - Prob. 60PCh. 2 - Prob. 61PCh. 2 - Prob. 62PCh. 2 - Prob. 63PCh. 2 - Prob. 64PCh. 2 - Prob. 65PCh. 2 - Prob. 67PCh. 2 - Prob. 68PCh. 2 - Prob. 69PCh. 2 - Prob. 70PCh. 2 - Prob. 71PCh. 2 - Prob. 72PCh. 2 - Prob. 73PCh. 2 - Prob. 74PCh. 2 - Prob. 75PCh. 2 - Prob. 76PCh. 2 - Prob. 77PCh. 2 - Prob. 78PCh. 2 - Prob. 79PCh. 2 - Prob. 80PCh. 2 - Prob. 81PCh. 2 - Prob. 82PCh. 2 - Prob. 83PCh. 2 - Prob. 84PCh. 2 - Prob. 85PCh. 2 - Prob. 86PCh. 2 - Prob. 87PCh. 2 - Prob. 88PCh. 2 - Prob. 89PCh. 2 - Prob. 90PCh. 2 - Prob. 91PCh. 2 - Prob. 1GSCh. 2 - Prob. 2GSCh. 2 - Prob. 3GS
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- Duchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brother has Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele?c. If your father’s brother had the disease, what is the probability that you have received the allele?arrow_forwarda. On the basis of this pedigree, what is the most likely mode of inheritance for the disease? Explain your reasoning. b. Based your answer to part a, give the most likely genotypes for all family members in the pedigree.arrow_forwardSickle cell anemia is an inherited red blood cell disorder in which there are not enough healthy red blood cells to carry oxygen throughout the body. The allele that causes sickle-cell anemia is autosomal recessive (s), and the dominant allele can be represented by S. How many offspring will be affected by the disorder if the mother is a carrier, and the father appears to be normal? (Include the gender) a. b. How many will become carriers? (include the gender) A- 三三三 四 四 II !!arrow_forward
- Phenylketonuria (PKU) is a disease that results from a recessive gene. Suppose that two unaffected parents produce a child with PKU. a. What is the probability that a sperm from the father will contain the PKU allele? b. What is the probability that an egg from the mother will contain the PKU allele? c. What is the probability that their next child will have PKU? d. What is the probability that their next child will be heterozygous for the PKU gene?arrow_forwardPhenylketonuria (PKU) is a disease that results from a recessive gene.Suppose that two unaffected parents produce a child with PKU. a. What is the probability that a sperm from the father will contain the PKU allele?b. What is the probability that an egg from the mother will contain the PKU allele?c. What is the probability that their next child will have PKU?d. What is the probability that their next child will be heterozygous for the PKU gene?arrow_forwardAssume that one of Merida's sons, who is heterozygous for orange hair color, married a girl that was also heterozygous. Create a Punnett square to show the possibilities that would result if they had children. a. List the possible genotypes and phenotypes for their children. b. What are the chances of a child with orange hair? c. What are the chantes of a child with yellow?arrow_forward
- A woman with a rare autosomal recessive disorder was told that it was unlikely that her children would have the disorderas her husband did not have it. However, her first child has the disorder. a. What is the most likely explanation? b. Diagram the cross between the woman and her husband using a Punnett square, give the genotypic ratio (GR) and phenotypic ratio (PR) from the Punnett square. c. Based on the Punnett square results, what is the chance that her next child will have the disorder?arrow_forwardBlood types in humans are Codominant. a. What are the possible genotypes of someone with type O blood? b. What are the possible genotypes of someone with type B blood? c. What is the phenotype of someone’s whose genotype is AO? d. A man with AB blood is married to a woman with AB blood. What blood types will their children be and in what proportion?arrow_forwardPLEASE ANSWER PART C.arrow_forward
- Give typing answer with explanation and conclusion The father of Mr Spock, first officer of the starship Enterprise, came from planet Vulcan; Spock’s mother came from Earth. A Vulcan has pointed ears (P), adrenals absent (A), and a right-sided double heart (R). All these alleles are dominant to Earth alleles. The three loci are autosomal, and they are linked as shown: --P----- 15 mu -----A-------- 20 mu --------R— Here's the new twist: having Vulcan adrenals and a human heart is an embryonic lethal combination, which will distort the proportion of the various phenotypes. If Mr Spock marries an Earth woman and there is no genetic interference, what proportion (0…1.0) of their children will have the phenotypes: A. Human ears, Vulcan heart, human adrenals B. Human ears, human heart, Vulcan adrenals C. Vulcan ears, Vulcan heart, Vulcan adrenals D. Vulcan ears, human heart, human adrenalsarrow_forwardA. Identify the pattern of inheritance in the pedigree below. B. Provide two pieces of evidence that you used to come to this conclusion. C. Identify the genotypes of individuals II-1 and III-2 (at the arrows)arrow_forwardBelow is a pedigree of a family with a rare genetic disorder. I. IV. a. What is the mode of inheritance for this rare disorder and what is the genotype of I.1 and 1.2? b. Write the genotypes for the following individuals (if the genotype is unknown write all possible genotypes): i.) III.2 - ii) III.3 -arrow_forward
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