Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 2, Problem 3Q
Summary Introduction
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The estimate of the average mass of a mitochondrion, considering the fact that mitochondria occupy 20% of the volume in the human body and there are 1
Introduction:
The mitochondria aredouble-membraned cell organelles, which act as the main site for the aerobic
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Pyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvatedehydrogenase complex, resulting in acetyl-CoA and CO2. Provide a full mechanismfor this reaction utilizing the TPP cofactor. Include the roles of all cofactors.
B- Vitamins are converted readily into important metabolic cofactors. Deficiency inany one of them has serious side effects.
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b. What would you expect the effect on the TCA intermediates for a patientsuffering from vitamin B 5 deficiency?
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Draw the Krebs Cycle and show the entry points for the amino acids Alanine,Glutamic Acid, Asparagine, and Valine into the Krebs Cycle - (Draw the Mechanism).
How many rounds of Krebs will be required to waste all Carbons of Glutamic Acidas CO2?
Chapter 2 Solutions
Biochemistry, The Molecular Basis of Life, 6th Edition
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