Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 2, Problem 42RQ
Summary Introduction
To review:
The structural and functional properties/characteristics of NPC (nuclear pore complex).
Introduction:
The fusion of inner and outer nuclear membrane results in the formation of nuclear pores in the nucleus of eukaryotic cells. These are macromolecular structures which help in regulating the traffic of molecules between the nucleus of the cell and its cytoplasm.
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Pyruvate is accepted into the TCA cycle by a “feeder” reaction using the pyruvatedehydrogenase complex, resulting in acetyl-CoA and CO2. Provide a full mechanismfor this reaction utilizing the TPP cofactor. Include the roles of all cofactors.
B- Vitamins are converted readily into important metabolic cofactors. Deficiency inany one of them has serious side effects.
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Draw the Krebs Cycle and show the entry points for the amino acids Alanine,Glutamic Acid, Asparagine, and Valine into the Krebs Cycle - (Draw the Mechanism).
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Chapter 2 Solutions
Biochemistry, The Molecular Basis of Life, 6th Edition
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