Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 2, Problem 42RQ
Summary Introduction
To review:
The structural and functional properties/characteristics of NPC (nuclear pore complex).
Introduction:
The fusion of inner and outer nuclear membrane results in the formation of nuclear pores in the nucleus of eukaryotic cells. These are macromolecular structures which help in regulating the traffic of molecules between the nucleus of the cell and its cytoplasm.
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Chapter 2 Solutions
Biochemistry, The Molecular Basis of Life, 6th Edition
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- An ATP-coupled transporter is used to import 1 phosphate from the extracellular environment. Intracellular phosphate exists at 65mM, while it is 2mM outside.Assume a free energy change of ATP hydrolysis of -42.7 kJ/mol. What is the net free energy change of the coupled reaction? Assume a membrane potential of 70mV.arrow_forwardAnother transporter brings 3 chloride ions into the cell. Outside, chloride has a concentration of 107mM, and 4mM inside the cell. Assuming a membrane potential of 62mV (negative inside), what is the free energy of transport of these ions?arrow_forwardFor the Oxaloacetate -> Malate reaction, assume the normal ratio of NAD/NADH, what is the maximum ratio of Malate/Oxaloacetate that will allow reaction progress?arrow_forward
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