Biochemistry
6th Edition
ISBN: 9781305577206
Author: Reginald H. Garrett, Charles M. Grisham
Publisher: Cengage Learning
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 17, Problem 8P
How Is
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Help
Metabolic flux is regulated by both availability of substrates and level of
enzyme activity. Match the mechanism by which enzyme activity is regulated
(A, B, C) with a specific example of this type of regulation (1, 2, 3, 4, 5, 6).
Each mechanism is associated with two specific examples.
Mechanism of Regulation
A. Catalytic activity
B. Compartmentation
C. Enzyme levels
A:1,5; B:3,4; C:2,6
OA:1,5; B:3,6; C:2,4
A:2,5: B:3.4. C.16
Example of
Regulation
1. covalent
modification
4. subcellular
localization
2. protein synthesis 5. allosteric control
3. tissue
localization
6. gene transcription
Discuss the role of enzymes in metabolic regulation by describing the following mechanisms.11.1Cellular compartmentalization 11.2 Covalent modification11.3 Zymogens
Chapter 17 Solutions
Biochemistry
Ch. 17 - Global Carbon Dioxide Cycling Expressed as Human...Ch. 17 - Prob. 2PCh. 17 - Where Do the O Atoms in Organisms Come From? Name...Ch. 17 - How Do Catabolism and Anabolism Differ? What are...Ch. 17 - How Art the Enzymes of Metabolic Pathways...Ch. 17 - Why Do Anabolic and Catabolic Pathways Differ? Why...Ch. 17 - Prob. 7PCh. 17 - How Is Metabolism Regulated? (Integrates with...Ch. 17 - Prob. 9PCh. 17 - Prob. 10P
Ch. 17 - Which Is “Better: NMR or MS? Compare and...Ch. 17 - How Do Vitamin-Derived Coenzymes Aid Metabolism?...Ch. 17 - What Art the Features of the Series of -omes?...Ch. 17 - Prob. 14PCh. 17 - Prob. 15PCh. 17 - Prob. 16PCh. 17 - Prob. 17PCh. 17 - Prob. 18PCh. 17 - Which of the following experimental approaches is...Ch. 17 - Prob. 20P
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biochemistry and related others by exploring similar questions and additional content below.Similar questions
- Please answer these biochemistry questions and briefly explain 1. Which is false about metabolic regulation? A: reactions with a large negative delta G are likely to be regulated B: reactions that require ATP are regulated C: glucagon and epineprine both stimulate glycogen breakdown D: all steps of all metabolic processes under strict regulation I picked D since all steps require sple extent of regulation however, "strict" regulation is limited to the irreversible steps 2. which is not a redox reaction in electron transport chain? A: Fe-S accepts e- from NADH B: reiske protein accepts e- from QH2 3. true or false: proton motive force is created through pumping H+ from matrix to inner membrane I put false, isnt the opposite true? pumping H+ from IMM to matrixarrow_forwardDiscuss the role of enzymes in metabolic regulation by describing the following five mechanisms.11.1Cascade systems11.2 Futile cycle11.3Cellular compartmentalization 11.4 Covalent modification11.5 Zymogensarrow_forward6. Reciprocal regulation of opposing pathways is necessary to avoid the wasteful synthesis anddegradation of metabolic intermediates. Provide two distinct examples of reciprocal regulation. Bespecific, and be sure to explain the conditions that signal enzyme activation and/or inhibition.arrow_forward
- The FMO3 enzyme has an important physiological function in people. State the normal substrate of FMO3 in people and describe a genetic polymorphism that can reduce the activity of this enzyme. Describe the consequence to people with the reduced FMO3 activity. Give at least one reference from the primary literature (i.e. a scientific journal) to support your answer.arrow_forwardAll metabolic pathways must be regulated to maintain homeostasis. The catalytic activity of anenzyme can be controlled allosterically and/or by reversible covalent modification. Provide anexample of each type of regulation (allosteric and reversible covalent modification) in the contextof a metabolic pathway. Be specific, and be sure to explain the rationale behind the regulatorystrategy.arrow_forwardAAUP NIN) May Time le In the central metabolic processes, the following statement is true: O a. Nonspontaneous processes have a positive delta G O b. Nonspontaneous processes can happen alone if an enzyme is present. O c. Spontaneous processes have a positive delta G O d. Spontaneous processes are usually reversible April 26 (Glycolysis.arrow_forward
- i submitted this 3 times in bartleby and everyone gave differnt answers please answer correctlyarrow_forwardPart II - Lactase Catalyzes the Hydrolysis of Lactose II.i-Enzymes and Sugars The group of college students is on their way to the ice-cream shop and Sanjeet has offered Xiao-Ma Lactaid so that she could go with the group and also eat ice cream despite her lactose intolerance. Xiao-Ma: I've never taken Lactaid. What is it? Sanjeet: Chris: Sanjeet: My mom told me that you become intolerant to dairy because you don't have the enzyme that can digest lactose, which is the sugar found in milk products. Lactaid is a dietary supplement that contains the lactase enzyme. Uh, Sanjeet, remember-I'm a literature major. What's an enzyme? I don't remember what that word really means. Also, is the sugar in the milk different from the other sugar in my food? Finally my biochem class comes in handy in real life! An enzyme is a protein which catalyzes a reaction in the cell. There are tons of different enzymes in your body. The lactase enzyme catalyzes the degrada- tion of lactose into its subunits.…arrow_forwardEnzymes act by reducing the activation energy of areaction. Describe several ways in which this isaccomplished.arrow_forward
- Which of the following is a primary function of the active site of an enzyme? a. It binds allosteric regulators of the enzyme. b. It binds noncompetitive inhibitors of the enzyme. c. It catalyzes the reaction associated with the enzyme. d. It is activated by the presence of the end product of the metabolic pathway in which the enzyme is involved. Clear my choice Question 2 Not yet answered Points out of 2.00 Flag question Question text Which of the following statement about the mass spectrometry is true? a. Large amount of protein sample is needed for mass spectrum, and thus it is very expensive. b. It is a powerful method to determine the 3-dimensional structure of proteins. c. It can be sued for protein location in a living cell. d. It can be used to measure the molecular weight of proteins. e. It can be used to determine the stability of a protein structure in solution. Clear my choice…arrow_forwardI have a project to construct a poster with the pathways that we have discussed in class which include glycolysis to beta-oxidation of fatty acids that are depicted inside a cell. I need to include reactions that are regulated, ones that produce or consume energy, and those at branch points between pathways. I also need a list of regulated enzymes and what regulates them. I also need to include intracellular membranes and locate reactions in the appropriate subcellular location. I can only include each metabolite once per subcellular location and include transporters. Any information that can be given to me on the different pathways and reactions would be helpful. I am at a loss and could use some help figuriong out what to put on my project. Thank youarrow_forwardDecide whether each of the following statements is true about leucine transaminase. It's an enzyme, and leucine is its substrate. It speeds up the rate at which leucine is converted to other substances. It's a small molecule, with a molecular weight around 50 mol If you were to write a chemical equation for certain biochemical reactions of leucine, leucine transaminase would appear on both sides. Otrue Ofalse Otrue Ofalse Otrue Ofalse Otrue Ofalse Xarrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
BiochemistryBiochemistryISBN:9781319114671Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.Publisher:W. H. Freeman
Lehninger Principles of BiochemistryBiochemistryISBN:9781464126116Author:David L. Nelson, Michael M. CoxPublisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...BiochemistryISBN:9781118918401Author:Donald Voet, Judith G. Voet, Charlotte W. PrattPublisher:WILEY
BiochemistryBiochemistryISBN:9781305961135Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougalPublisher:Cengage Learning
BiochemistryBiochemistryISBN:9781305577206Author:Reginald H. Garrett, Charles M. GrishamPublisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...BiochemistryISBN:9780134015187Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. PetersonPublisher:PEARSON
Biochemistry
Biochemistry
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:W. H. Freeman
Lehninger Principles of Biochemistry
Biochemistry
ISBN:9781464126116
Author:David L. Nelson, Michael M. Cox
Publisher:W. H. Freeman
Fundamentals of Biochemistry: Life at the Molecul...
Biochemistry
ISBN:9781118918401
Author:Donald Voet, Judith G. Voet, Charlotte W. Pratt
Publisher:WILEY
Biochemistry
Biochemistry
ISBN:9781305961135
Author:Mary K. Campbell, Shawn O. Farrell, Owen M. McDougal
Publisher:Cengage Learning
Biochemistry
Biochemistry
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Cengage Learning
Fundamentals of General, Organic, and Biological ...
Biochemistry
ISBN:9780134015187
Author:John E. McMurry, David S. Ballantine, Carl A. Hoeger, Virginia E. Peterson
Publisher:PEARSON
Anaerobic Respiration; Author: Bozeman Science;https://www.youtube.com/watch?v=cDC29iBxb3w;License: Standard YouTube License, CC-BY