Chapter 17, Problem 17.53P

Interpretation Introduction

Interpretation:

The last step in a synthesis of fexofenadine has to be completed.

Concept introduction:

$NaB{H}_4$- Sodium borohydride:

• This is a selective reducing agent but less reactive than $LiAl{H}_4$
• It is only powerful enough to reduce aldehydes, ketones and acid chlorides to alcohols.
• It cannot reduce acids, amides , nitriles and esters properly.
• $LiAl{H}_4$ can reduce aldehyde to primary alcohol and ketone to secondary alcohol.