Biology 2e
2nd Edition
ISBN: 9781947172517
Author: Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher: OpenStax
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Textbook Question
Chapter 17, Problem 10RQ
Linkage analysis.
- is used to create a physical map
- is based on the natural recombination process
- requires radiation hybrid mapping
- involves breaking and rejoining of DNA artificially
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Regarding STR markers used in forensic science. Tick all the correct statements:
no correct statement
the PCR primers used to amplify STRs are located in the repeat units
PCR primers to amplify STRs are located on both sides of the repeat units
the PCR primers used to amplify STRs are coupled to a fluorochrome which is essential for the detection of amplicons
they are absent from the gonosomes
the allelic frequencies of STR markers vary according to the ethnicity of the individuals genotyped
they are present homogeneously throughout the nuclear genome
Why does the probe bind to a specific site on a chromosome?
Place the steps of the double-strand break model of recombination in order.
DNA polymerase fills in gaps in the DNA
exonuclease generates 3' single-stranded overhangs
DNA ligase seals the nicked DNA
First step
Last step
Answer Bank
homologous region of intact homolog is invaded by free end
endonuclease cleaves both strands of one homolog
Chapter 17 Solutions
Biology 2e
Ch. 17 - Figure 17.7 You are working in a molecular biology...Ch. 17 - Figure 17.8 Do you think Dolly was a Finn-Dorset...Ch. 17 - Figure 17.15 In 2011, the United States...Ch. 17 - GMOs are created by. generating genomic DNA...Ch. 17 - Gene therapy can be used to introduce foreign DNA...Ch. 17 - Insulin produced by molecular cloning is of pig...Ch. 17 - Bt toxin is considered to be. a gene for modifying...Ch. 17 - The Flavr Savr Tomato: is a variety of...Ch. 17 - generated after a cDNA library is made unique...Ch. 17 - Linkage analysis. is used to create a physical map...
Ch. 17 - Genetic recombination occurs by which process?...Ch. 17 - Individual genetic maps in a given species are:...Ch. 17 - Information obtained by microscopic analysis of...Ch. 17 - The chain termination method of sequencing uses...Ch. 17 - Whole-genome sequencing can be used for advances...Ch. 17 - Sequencing an individual person’s genome is...Ch. 17 - What is the most challenging issue facing genome...Ch. 17 - Genomics can be used in agriculture to generate...Ch. 17 - Genomics cam be used on a personal level to:...Ch. 17 - What is a biomarker? the color coding of different...Ch. 17 - A protein signature is: the path followed by a...Ch. 17 - Describe the precess of Southern blottingCh. 17 - A researcher wants to study cancer cells from a...Ch. 17 - How would a scientist introduce a gene for...Ch. 17 - If you had a chance to get your genome sequenced,...Ch. 17 - Why is so much effort being poured into genome...Ch. 17 - How could a genetic map of the human genome help...Ch. 17 - Explain why metagenomics is probably the most...Ch. 17 - How can genomics be used to predict disease risk...Ch. 17 - How has proteomics been used in cancer detection...Ch. 17 - What is personalized medicine?
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- Select the characteristics/descriptions of DNA polymerase. Select ALL that apply requires a primer adds nucleotides to 3' end of DNA strand adds nucleotides to 5' end of DNA strand does not require primer has 3'-to-5' exonuclease activity that allows "proofreading" of DNA strand being madearrow_forwardWhich of the following is/are true of DNA general recombination? The process involves invasion of a single-stranded DNA with a free 3'-end into a DNA duplex with the same sequence (on one strand) The process involves formation and resolution of a Holliday structure. The process involves use of a restriction endonuclease. The process involves synthesis of DNA by DNA polymerase.arrow_forwardThe primary benefit of recombination is: Activity of mobile genetic elements Meiotic recombination DNA double-strand break repair Movement of viruses between lytic and prophage phases Bacterial control of gene expressionarrow_forward
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