Genetics: Analysis and Principles
5th Edition
ISBN: 9780073525341
Author: Robert J. Brooker Professor Dr.
Publisher: McGraw-Hill Education
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Chapter 16, Problem 5CONQ
Summary Introduction
To analyze:
Epigenetic changes may be encodedin development, or they may be produced by environmental factors.
From the given examples, question is asked to identify the modifications that areencoded in the development, and modifications that are produced by environmental factors.
a) Imprinting of
b) Development of queen and worker honeybees.
c) X-chromosome inactivation in mammals.
d) Development of cancer.
Introduction:
Epigenetic changes occur in development; these changes are reversible. Mainly, non-coding RNA and transcription factorsare involved in these processes; they recruit some proteins which carry out modification on DNA i.e. silencing and expression of specific coding sequence. It is an important event that inhibits the unnecessary expression of protein.
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19. On the diagram below
a. Label the three pictures as: DNA; polypeptide; or RNA.
b. Label the arrows as: translation or transcription/RNA processing.
c. Add the following details to the diagram.
Promoter region
TATA box
Transcription start site
Transcription terminator
Intron (A,B,C,D)
Exons (1,2,3,4,5)
Splice sites
5' cap
5' UTR (untranslated region)
3' poly A tail
3' UTR (untranslated region)
Translational start (AUG)
Translational stop (UGA, UAG, or UAA)
N and C ends of polypeptide
0000
Chapter 16 Solutions
Genetics: Analysis and Principles
Ch. 16.1 - Which of the following are examples of molecular...Ch. 16.1 - 2. An epigenetic modification to a specific gene...Ch. 16.1 - Prob. 3COMQCh. 16.1 - Epigenetic changes may a. be programmed during...Ch. 16.2 - 1. For the Igf2 gene, where do de novo methylation...Ch. 16.2 - 2. For XCI to occur, where are the Xist and Tsix...Ch. 16.2 - 3. Which of the following possibilities could...Ch. 16.3 - 1. When mice carrying theallele exhibit a darker...Ch. 16.3 - Which of the following types of epigenetic changes...Ch. 16.4 - Prob. 1COMQ
Ch. 16.4 - Prob. 2COMQCh. 16.4 - Prob. 3COMQCh. 16.4 - Prob. 4COMQCh. 16 - Prob. 1CONQCh. 16 - List and briefly describe five types of molecular...Ch. 16 - Prob. 3CONQCh. 16 - What is the key difference between cis and...Ch. 16 - Prob. 6CONQCh. 16 - Prob. 7CONQCh. 16 - 7. Outline the molecular steps in the process of...Ch. 16 - Prob. 9CONQCh. 16 - 9. In general, explain how epigenetic...Ch. 16 - 10. What are the contrasting roles of trithorax...Ch. 16 - Describe the molecular steps by which polycomb...Ch. 16 - Prob. 13CONQCh. 16 - Using coat color in mice and the development of...Ch. 16 - How can environmental agents that do not cause...Ch. 16 - Prob. 5CONQCh. 16 - Define alternative splicing. What are advantages...Ch. 16 - What is the function of a splicing factor? Explain...Ch. 16 - Figure 16.8 shows the products of alternative...Ch. 16 - Lets suppose a person is homozygous for a mutation...Ch. 16 - Prob. 20CONQCh. 16 - What are the advantages and disadvantages of mRNAs...Ch. 16 - Prob. 22CONQCh. 16 - Prob. 23CONQCh. 16 - Prob. 24CONQCh. 16 - Describe how the binding of the iron regulatory...Ch. 16 - Prob. 1EQCh. 16 - In the experiments described in Figure 16.8,...Ch. 16 - Prob. 3EQCh. 16 - A research study indicated that an agent in...Ch. 16 - Lets suppose you were interested in developing...Ch. 16 - E6. In Experiment 16A by Fire and Mello, were they...Ch. 16 - E7. Explain how the data of Fire and Mello...Ch. 16 - Prob. 8EQCh. 16 - 2. Discuss the similarities and differences of...Ch. 16 - How are regulatory transcription factors...
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