Biochemistry: The Molecular Basis of Life
6th Edition
ISBN: 9780190209896
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 16, Problem 46SA
Summary Introduction
To review:
The common symptom of leptin deficiency and Prader–Willi syndrome.
Introduction:
A syndrome can be defined as a group of medical symptoms that are often related to a particular disease or disorder. Generally, the symptoms are specific to a particular disease. However, it is not always true. There are certain symptoms that are common to other diseases also.
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Two melanocyte-stimulating hormones have the following amino acid sequences. Take a highlighter or
colored pencil, and figure out how much of the sequence the porcine MSH has in common with the human
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beta-MSH (human): Ala-Glu-Lys-Lys-Asp-Glu-Gly-Pro-Tyr-Arg-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp
beta-MSH (porcine): Asp-Glu-Gly-Pro-Tyr-Lys-Met-Glu-His-Phe-Arg-Trp-Gly-Ser-Pro-Pro-Lys-Asp
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(why?)?
and
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Chapter 16 Solutions
Biochemistry: The Molecular Basis of Life
Ch. 16 - Prob. 1QCh. 16 - Prob. 2QCh. 16 - Prob. 3QCh. 16 - Prob. 4QCh. 16 - Prob. 5QCh. 16 - Prob. 6QCh. 16 - Prob. 7QCh. 16 - Prob. 8QCh. 16 - Prob. 1RQCh. 16 - Prob. 2RQ
Ch. 16 - Prob. 3RQCh. 16 - Prob. 4RQCh. 16 - Prob. 5RQCh. 16 - Prob. 6RQCh. 16 - Prob. 7RQCh. 16 - Prob. 8RQCh. 16 - Prob. 9RQCh. 16 - Prob. 10RQCh. 16 - Prob. 11RQCh. 16 - Prob. 12RQCh. 16 - Prob. 13RQCh. 16 - Prob. 14RQCh. 16 - Prob. 15RQCh. 16 - Prob. 16RQCh. 16 - Prob. 17RQCh. 16 - Prob. 18RQCh. 16 - Prob. 19RQCh. 16 - Prob. 20RQCh. 16 - Prob. 21RQCh. 16 - Prob. 22RQCh. 16 - Prob. 23RQCh. 16 - Prob. 24RQCh. 16 - Prob. 25RQCh. 16 - Prob. 26RQCh. 16 - Prob. 27RQCh. 16 - Prob. 28RQCh. 16 - Prob. 29RQCh. 16 - Prob. 30RQCh. 16 - Prob. 31RQCh. 16 - Prob. 32RQCh. 16 - Prob. 33RQCh. 16 - Prob. 34FBCh. 16 - Prob. 35FBCh. 16 - Prob. 36FBCh. 16 - Prob. 37FBCh. 16 - Prob. 38FBCh. 16 - Prob. 39FBCh. 16 - Prob. 40FBCh. 16 - Prob. 41FBCh. 16 - Prob. 42FBCh. 16 - Prob. 43FBCh. 16 - Prob. 44SACh. 16 - Prob. 45SACh. 16 - Prob. 46SACh. 16 - Prob. 47SACh. 16 - Prob. 48SACh. 16 - Prob. 49TQCh. 16 - Prob. 50TQCh. 16 - Prob. 51TQCh. 16 - Prob. 52TQCh. 16 - Prob. 53TQCh. 16 - Prob. 54TQCh. 16 - Prob. 55TQCh. 16 - Prob. 56TQCh. 16 - Prob. 57TQCh. 16 - Prob. 58TQCh. 16 - Prob. 59TQCh. 16 - Prob. 60TQCh. 16 - Prob. 61TQCh. 16 - Prob. 62TQCh. 16 - Prob. 63TQCh. 16 - Prob. 64TQCh. 16 - Prob. 65TQCh. 16 - Prob. 66TQCh. 16 - Prob. 67TQCh. 16 - Prob. 68TQCh. 16 - Prob. 69TQCh. 16 - Prob. 70TQCh. 16 - Prob. 71TQCh. 16 - Prob. 72TQCh. 16 - Prob. 73TQCh. 16 - Prob. 74TQCh. 16 - Prob. 75TQ
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- Which amino acid pair constitutes the hydrophobic patch on sickle cell hemoglobin that results in formation of protein oligomers with the Glu 6 --> Val 6 sickle cell mutation? Does normal hemoglobin contain this same amino acid pair constituting a hydrophobic patch? Phe 85 / Leu 88; no Phe 85 / Leu 88; yes Trp 85 / Leu 88; yes Olle 85 / Leu 88; yes Pro 85 / Lys 88; noarrow_forwardWhat do you mean by hypoacetylation of lysines?arrow_forwardWhat are the differences between synthesis of phosphatidylethanolamine in prokaryotes and eukaryotes?arrow_forward
- The melanocyte-stimulating hormone a-melanotropin has the following sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val In the one-letter code of amino acids, this sequence would be: SYSMEHFRWGKPV STSMGHFAWGKPV O SYSMDHFAWGKPV O SYSMEHFAWGLPVarrow_forwardWhat are statins? Name the microorganism that produces this substance. How is it medically important?arrow_forwardWhat is the reason why "AUTOcoids" changed to AUTACOIDS? Are there implication of the change?arrow_forward
- Why do both thymine and uracil specify the incorporation of adenine?arrow_forwardWhat type of protein does FOG2 produce?arrow_forwardSubjecting this peptide to trypsin would result in L-M-F-V-W-E-Q-A-P-S-P O A. Lys and Met-Phe-Val-Trp-Glu-Gln-Arg and Pro-Ser-Pro OB, Leu-Met-Phe-Val-Trp-Glu-Gin-Ala-Pro-Ser-Pro Leu and Met-Phe-Val-Trp-Glu-Gln-Arg-Pro-Ser-Pro OC. Op. Lys and Met-Phe-Val-Trp-Glu-Gln-Ala-Pro-Ser-Pro Leu and Met-Phe-Val-Trp-Glu-Gin-Arg-Pro-Ser-Pro OE.arrow_forward
- The neighboring amino acid that TYR 368 interacts with is ILE 160. What are the properties of the amino acid ILE 160?arrow_forwardWhat do you observe about similarities and differences in terms of secondary and tertiary structures between human and bovine chymotrypsin?arrow_forwardAn individual with an argininosuccinase deficiency is administered benzoate and arginine. This individual will have their nitrogen removed from the body as which of the following compounds? SELECT ALL ANSWERS THAT APPLY. ** This is NOT a multiple choice question! ** O. hippurate O II. phenylacetylglutamine O I. citrulline OV. carbamoyl phosphate Ov. argininosuccinate O VI. arginine OVI. fumarate O VII. benzoylglycinearrow_forward
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