A geneticist is attempting to isolate mutations in the genes for four enzymes acting in a metabolic pathway in the bacterium Escherichia coli. Developing a hypothesis to explain that the geneticist has been able to isolate mutations in the genes for enzymes 1 and 2, but not for enzymes 3 and 4. Introduction: Enzymes are the proteins coded by genes (sequence of nucleotides) present in DNA (Deoxyribonucleic acid). Different genes code for different enzymes in the cell. The enzyme binds to a substrate and subsequently forms a product. Gene is a sequence of nucleotides and if there is any change (mutation) in the nucleotide sequence of a gene coding for an enzyme; the enzyme formed will have some or all of its properties changed, depending upon the type of mutation.

Question

Want to see the full answer?

Answer 1

Question

Chapter 15, Problem 14TYK

Summary Introduction

To review:

A geneticist is attempting to isolate mutations in the genes for four enzymes acting in a metabolic pathway in the bacterium Escherichia coli. Developing a hypothesis to explain that the geneticist has been able to isolate mutations in the genes for enzymes 1 and 2, but not for enzymes 3 and 4.

Introduction:

Enzymes are the proteins coded by genes (sequence of nucleotides) present in DNA (Deoxyribonucleic acid). Different genes code for different enzymes in the cell. The enzyme binds to a substrate and subsequently forms a product. Gene is a sequence of nucleotides and if there is any change (mutation) in the nucleotide sequence of a gene coding for an enzyme; the enzyme formed will have some or all of its properties changed, depending upon the type of mutation.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Over several years, researchers learned more about proteins and the genes which code for them, the findings of which lead them to revise the original one gene-one enzyme hypothesis. Which of the following is NOT one of the findings which led to revision? a. many genes code can code for RNA molecules which never go on to produce a protein at all b. oftentimes, many genes are required to produce a single protein, where one gene produces one polypeptide and many polypeptides together make the single protein c. in addition to enzymes, gene products also include non-enzyme proteins like keratin and insulin d. a single gene produces one specific enzyme e. a single gene may code for multiple different (closely related) polypeptides

Galactosemia is a metabolic disorder characterized by the inability to metabolize the sugar galactose. People with galactosemia suffer from liver, kidney, and brain damage among other symptoms. A gene mutation underlying galactosemia was identified by sequencing the genome of a person with galactosemia. What additional evidence would support the hypothesis that the mutation in the candidate gene causes the disease?

Beadle and Tatum's experiments led to the "one gene - one enzyme (protein)" hypothesis. In subsequent years, many exceptions to this hypothesis were noted. A molecule of hemoglobin fails to support this hypothesis for which of the following reasons? n eukaryotes, one gene can code form multiple isoforms of a polypeptide. The functional hemoglobin protein is made from multiple polypeptides. Not all enzymes are proteins. Not all genes encode proteins.