Biology: The Dynamic Science (MindTap Course List)
4th Edition
ISBN: 9781305389892
Author: Peter J. Russell, Paul E. Hertz, Beverly McMillan
Publisher: Cengage Learning
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Chapter 15, Problem 3TYK
Summary Introduction
Introduction:
Translation is the process, in which the
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Formation of the 70S ribosomal initiation complex for prokaryotic translation requires:
a.tRNAfMet
b.tRNAMet
c.GTP
d.EF-Tu
e.IF-2
f.Mn2+
During the termination of translation, what is the correct polypeptide sequence which will be released by the ribosome?
5' - AUG - UAU - CUC - UUU - 3' (mRNA codon sequence)
3' - UAC - AUA - GAG - AAA - 5' (tRNA anticodon sequence)
A.START - Tyr - Leu - Phe
B. Tyr - Ile - Glu - Lys
C. START - Ile - Glu - Lys
D. Ser - Tyr - Gly - Cys
Find the events from prokaryotic translation from the list below and list them below in order, by letter, from earliest to latest during translation
A. Incoming tRNA occupies the A-site
B. Small ribosome binds to Shine Dalgarno sequence
C. 5’ methyl cap binds small ribosome
D. Large ribosome subunit binds the small ribosome subunit
E. P-site tRNA peptide is attached to the amino acid of the A-site tRNA.
F. f-Met tRNA binds to P site
G. Small ribosomal subunit binds mRNA
H. Peptide released from complex.
Chapter 15 Solutions
Biology: The Dynamic Science (MindTap Course List)
Ch. 15.1 - Prob. 1SBCh. 15.1 - If the codon were five bases long, how many...Ch. 15.2 - For the DNA template below, what would be the...Ch. 15.2 - Prob. 2SBCh. 15.3 - Prob. 1SBCh. 15.3 - Prob. 2SBCh. 15.4 - Prob. 1SBCh. 15.4 - Distinguish between the P, A, and E sites of the...Ch. 15.4 - Prob. 3SBCh. 15.5 - How does a missense mutation differ from a silent...
Ch. 15.5 - Prob. 2SBCh. 15.5 - Prob. 3SBCh. 15.5 - Prob. 4SBCh. 15 - Eukaryotic mRNA: usessnRNPs to cut out introns and...Ch. 15 - A segment of a strand of DNA has a base sequence...Ch. 15 - Prob. 3TYKCh. 15 - Prob. 4TYKCh. 15 - Which of the following statements is false? a. GTP...Ch. 15 - Prob. 6TYKCh. 15 - Prob. 7TYKCh. 15 - Prob. 8TYKCh. 15 - Prob. 9TYKCh. 15 - A part of an mRNA molecule with the sequence 5-UGC...Ch. 15 - Discuss Concepts A mutation occurs that alters an...Ch. 15 - Discuss Concepts The normal form of a gene...Ch. 15 - Prob. 13TYKCh. 15 - Prob. 14TYKCh. 15 - Prob. 15TYKCh. 15 - Prob. 16TYKCh. 15 - Prob. 17TYKCh. 15 - Prob. 1ITD
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- Examine the following base sequence – 5’ UGA 3’. It represents the anticodon region of a particular tRNA. Based on this knowledge you know that a. This tRNA would be used to stop translation. b. This tRNA would carry the amino acid Serine to the ribosome. c. This tRNA would carry the amino acid Threonine to the ribosome. d. This tRNA would bind a TCA codon on DNA. e. This tRNA would not carry any amino acid to the ribosome. f. This tRNA would carry the amino acid Leucine to the ribosome.arrow_forwardDuring translation, when a stop codon is read on the mRNA strand at the ribosome... a the mRNA is digested by a protease complex b a repressor attached to the ribosome that inhibits the movement of the ribosome along the mRNA c the enzyme helicase binds to terminate the polypeptide d a release factor enters the A site of the ribosome and stimulates the disassembly of the translation complex Codons are... a triplets coding for a single amino acid. b redundant in their coding for various amino acids. c matched with anticodons during translation d triplets found on transfer RNA Question 6 (1 point) In order to produce many copies of the same protein in a short period of time, the cell uses... a intron self-splicing. b many RNA polymerase molecules to produce multiple mRNA transcripts at the same time. c single-unit ribosomes for high speed translation. d codon-anticodon reciprocal…arrow_forwardWhich of the following is TRUE in translation? A. Amino acyl TRNA containing one amino acid is attached to the P site B. Amino acids/peptides attached to the amino acyl tRNA at the P site are transferred to amino acids at the A site, followed by translocation. C. Empty TRNAS are immediately released from the ribosomes D. The E site is always empty after translocation to receive incoming empty TRNAS. E. The anticodon binding to the codon is stringent, i.e. there must be complete complementary base-pairing between the bases in the codon and anticodon before translation can proceed.arrow_forward
- Tomats Provide the three-letter amino acid sequence expected from each of the following mRNA segments. a. 5'GGCAUCUACCGA3' b. 5'GUACGUCGGUUACCAACC3' D. What is the tRNA anticodon if the codon in mRNA is as follows? a. CGC b. ACA c. GAU d. UUCarrow_forwardResearchers are studying the mechanism of the antibiotic chloramphenicol. They know that it prevents the formation of peptide bonds during translation. A model of the translation process is shown in the diagram. Which of the following describes where in the model chloramphenicol acts to interfere with the production of proteins from DNA? A - during initiationB - during elongationC = during terminationD = during protein releasearrow_forwardThe following diagram illustrates a step in the process of translation. Identify the following elements on the diagram.arrow_forward
- You are studying a eukaryotic gene in which translation normally begins at the second AUG in the mRNA (underlined). The sequence surrounding both AUGs is CGGAUGCACAGGACAUCCUACCUACGGAGAUGA.... Predict the effects of the following mutations on the translation of this mRNA. Present the new sequence, highlight the changes in the sequence and consider the best context for translation. a. Change the first and second C to G b. Change the first and second C to G and also change the UAC codon before the second AUG to UAG.arrow_forwardthe following is a strand of a DNAarrow_forwardGiven is the 30 nucleotides in the human gene for hemoglobin (the oxygen-carrying protein in the red blood cells): 5’ TAC-CAC-GTG-GAC-TGA-GGA-CTC-CTC-TTC-AGA 3’ a. What is the complementary strand? b.Deduce the mRNA in this coding region. c.What is the amino acid sequence based on this mRNA? d. A very important mutation in human hemoglobin occurs in this DNA sequence, where the T at nucleotide 20 is replace with an A. The mutant hemoglobin is called sickle cell hemoglobin and is associated with severe anemia. What is the amino acid replacement that results in sickle-cell hemoglobin?arrow_forward
- What would be the direct consequence to a cell of loss-of-function of Elongation Factor-Tu (EF-Tu)? You may select multiple answers. a. tRNAs would fail to exit the E site after giving up their amino acid. b. The error rate of translation would increase. c. The ribosome would frequently fail to identify the correct start codon and initiation of translation would become less efficient. d. There would be no pause between the entry of a tRNA into the A site and peptidyl transfer.arrow_forwardUse the bank of terms listed to label all important structures of the diagram of the translation complex below. a. Polypeptide f. Anticodon . 140 b. Amino acids g. MRNA 131 c. tRNA h. 5' 139 d. Ribosome i 3 132 e. IRNA with amino acid attached j. codon Phe Gly 133 135 137 136 138 134 Use the word bank provided to complete the flowchart to show all the major parts of a vertebrate nervous system. central nervous system a. sympathetic nervous system b. brain 141 143 C. autonomic nervous system d. spinal cord e. parasympathetic nervous system peripheral 1. somatic nervous system 144 142 nervous system 145 146 sensory neurons motor neurons ......arrow_forwardFormation of the 70S ribosomal initiation complex for prokaryotic translation requires A. Mn2+ B. EF-Tu C. tRNAMet D. tRNAfMet D. IF-2 E. GTParrow_forward
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