Statistics for Business and Economics (13th Edition)
Statistics for Business and Economics (13th Edition)
13th Edition
ISBN: 9780134506593
Author: James T. McClave, P. George Benson, Terry Sincich
Publisher: PEARSON
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Chapter 13.4, Problem 13.13ACB

Active pharmaceutical ingredient. During the development of a new drug. pharmaceutical companies monitor the drug's active pharmaceutical ingredient (API). An article published in Organic Process Research & Development (July 2013) demonstrated the use of an individual control chart (x-chart) for this purpose. The data in the table represent API values for 53 consecutive batches of the new drug. (Note: Read across rows for consecutive API - measurements.) A Minitab printout with descriptive statistics for the data follows.

  1. a. Locate the mean and standard deviation of the sample data on the printout.
  2. b. Use the mean and standard deviation to find the center line and the upper and lower control limits for an x-chart of the data, as in Example 13.3” (p. 13-15).
  3. c. Plot the data in an x-chart Is the process in control? No

Chapter 13.4, Problem 13.13ACB, Active pharmaceutical ingredient. During the development of a new drug. pharmaceutical companies , example  1

Source: Based on K. Mukundam el al., “1-MR Control Chart: A Tool for Judging the Health of the Current Manufacturing Process of an API and for Setting the Trial Control Limits in Phase I of the Process Improvement.” Organic Procesa Research A Development. Vol. 17. July 2013 (Table 3).

Chapter 13.4, Problem 13.13ACB, Active pharmaceutical ingredient. During the development of a new drug. pharmaceutical companies , example  2

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Chapter 13 Solutions

Statistics for Business and Economics (13th Edition)

Ch. 13.4 - The data in the following table were collected for...Ch. 13.4 - Prob. 13.12ACBCh. 13.4 - Active pharmaceutical ingredient. During the...Ch. 13.4 - Detecting gender-related employment disparities....Ch. 13.4 - Pain levels of ICU patients. Various interventions...Ch. 13.4 - Quality control for irrigation data. Most farmers...Ch. 13.4 - Improving public health waiting times. Statistical...Ch. 13.4 - Cereal box manufacturing. A machine at K-Company...Ch. 13.4 - Detecting under-reported emissions. The...Ch. 13.4 - 13 20 Selecting the best wafer-slicing machine....Ch. 13.4 - Chunky data. BPI Consulting, a leading provider of...Ch. 13.4 - Military aircraft bolts. A precision parts...Ch. 13.5 - What characteristic of a process is an R-chart...Ch. 13.5 - Prob. 13.24LMCh. 13.5 - Use Table IX on page 13-74 to find the values of...Ch. 13.5 - Construct and interpret an R-chart for the data in...Ch. 13.5 - Construct and interpret an R-chart for the data in...Ch. 13.5 - Construct and interpret an R-chart and an x -chart...Ch. 13.5 - Weight of packed frozen scallops. In Quality...Ch. 13.5 - Detecting gender-related employment disparities....Ch. 13.5 - Pain levels of ICU patients. Refer to the Research...Ch. 13.5 - Quality control for irrigation data. Refer to...Ch. 13.5 - Lowering the thickness of an expensive blow-molded...Ch. 13.5 - Cola bottle filling process. A soft-drink bottling...Ch. 13.5 - Chunky data. Refer to Exercise 13.21e (p. 13-40)...Ch. 13.5 - Replacement times for lost ATM cards. In an effort...Ch. 13.5 - Military aircraft bolts. Refer to the...Ch. 13.5 - Precision of scale weight measurements. The...Ch. 13.6 - What characteristic of a process is a p-chart...Ch. 13.6 - In each of the following cases, use the sample...Ch. 13.6 - The proportion of defective items generated by a...Ch. 13.6 - To construct a p-chart for a manufacturing...Ch. 13.6 - To construct a p-chart, 20 samples of size 150...Ch. 13.6 - Academic failure rates in Nigeria. The quality...Ch. 13.6 - Monitoring surgery complications. An article on...Ch. 13.6 - Rental car call center study. A worldwide rental...Ch. 13.6 - Defective micron chips. A manufacturer produces...Ch. 13.6 - Hand break cable defects. In Control Engineering...Ch. 13.6 - Monitoring newspaper typesetters. Accurate...Ch. 13.6 - Quality of rewritable CDs. A Japanese compact disc...Ch. 13.6 - Leaky process pumps. Quality (February 2008)...Ch. 13.6 - Rubber company lire tests. Goodstone Tire Rubber...Ch. 13.7 - Explain why it is inappropriate to conduct a...Ch. 13.7 - Explain the difference between process spread and...Ch. 13.7 - Describe two different ways to assess the...Ch. 13.7 - Why is it recommended to use and interpret Cp in...Ch. 13.7 - For a process that is in control and follows a...Ch. 13.7 - Find the specification spread for each of the...Ch. 13.7 - Find (or estimate) the process spread for each of...Ch. 13.7 - Find the value of Cp for each of the following...Ch. 13.7 - Upper specification limit of a process. An...Ch. 13.7 - Capability of an in-control process. A process is...Ch. 13.7 - Water use at a thermal power plant. Thermal power...Ch. 13.7 - Cereal box filling process. Refer to the data on...Ch. 13.7 - Military aircraft bolts. Refer to Exercise 13.22...Ch. 13.7 - Bioreactor production of antibodies. Benchtop...Ch. 13.7 - Driver gear bore holes. During the manufacture of...Ch. 13.7 - Lowering the thickness of an expensive blow-molded...Ch. 13 - Define quality and list its important dimensions.Ch. 13 - What is a process? Give an example of an...Ch. 13 - What is a system? Give an example of a system with...Ch. 13 - Describe the six major sources of process...Ch. 13 - Suppose all the output of a process over the last...Ch. 13 - Processes that are in control are predictable;...Ch. 13 - Compare and contrast special and common causes...Ch. 13 - Explain the difference between control limits and...Ch. 13 - Should control charts be used to monitor a process...Ch. 13 - Under what circumstances is it appropriate to use...Ch. 13 - A process is under control and follows a normal...Ch. 13 - Weight of a product. Consider the time series data...Ch. 13 - Lengths of pencils. The length measurements of 20...Ch. 13 - Applying pattern-analysis rules. Use the...Ch. 13 - Defective plastic mold. A company that...Ch. 13 - Robotics clamp gap width. Control chart...Ch. 13 - Package sorting time. AirExpress. an overnight...Ch. 13 - Waiting times of airline passengers. Officials at...Ch. 13 - Defects in graphite shafts. Over the last year, a...Ch. 13 - New iron-making process. Mining Engineering...Ch. 13 - CPU of a computer chip. The central processing...Ch. 13 - Bayfield Mud Company case. The text Quantitative...
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