Genetic Analysis: An Integrated Approach (2nd Edition)
2nd Edition
ISBN: 9780321948908
Author: Mark F. Sanders, John L. Bowman
Publisher: PEARSON
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Chapter 13, Problem 19P
A boy with Down syndrome (trisomy
Explain how this is possible.
How many chromosomes do you expect to see in karyotypes of the parents?
What term best describes this kind of chromosome abnormality?
What is the probability the next child of this couple will have a normal phenotype and have
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Chapter 13 Solutions
Genetic Analysis: An Integrated Approach (2nd Edition)
Ch. 13 - Prob. 1PCh. 13 - For one set of chromosomes carried by a triploid...Ch. 13 - 10.8 If the haploid number for a plant species is...Ch. 13 - From the following list, identify the types...Ch. 13 - Mating between a male donkey (2n=64) and a female...Ch. 13 - Prob. 6PCh. 13 - Prob. 7PCh. 13 - What can we conclude about a mutational event...Ch. 13 - 9. In terms of the chromosome content of nuclei,...Ch. 13 - 10. In Drosophila, an X-linked recessive allele...
Ch. 13 - The plants in this problem are the same as those...Ch. 13 - A normal chromosome and its homolog carrying a...Ch. 13 - 10.12 A pair of homologous chromosomes in...Ch. 13 - 10.13 An animal heterozygous for a reciprocal...Ch. 13 - Dr. Ara B. Dopsis has an idea he thinks will be a...Ch. 13 - Suppose polymerase chain reaction (PCR) is used...Ch. 13 - Prob. 17PCh. 13 - A healthy couple with a history of three previous...Ch. 13 - A boy with Down syndrome (trisomy 21) has 46...Ch. 13 - Prob. 20PCh. 13 - 10.28 A small population of deer living on an...Ch. 13 - In humans that XX/XO mosaics, the phenotype is...Ch. 13 - 10.20 A plant breeder would like to develop the...Ch. 13 - In Drosophilia, seven partial deletion (1to7)...Ch. 13 - Two experimental varieties of strawberry are...Ch. 13 - 10.23 In the tomato, Solanum esculentum, tall ()...Ch. 13 - In Drosophila, the wild-type red eye color is...Ch. 13 - A DrosophilaPelement 2.5kb in length is modified...Ch. 13 - A biologist studying flight mechanisms in insects...Ch. 13 - 30. After reading Experimental Insight and...Ch. 13 - 31. Two NotI restriction enzymes cleave DNA on...Ch. 13 - For the following crosses, determine as accurately...
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- Given the karyotype shown at right, is this a male or a female? Normal or abnormal? What would the phenotype of this individual be?arrow_forwardIn the fruit fly Drosophila melanogaster, a recessive condition called eyeless (ey) significantly interferes with normal eye development. Eyes are either very small or absent. The ey gene is found on chromosome 4, which is the smallest of the four chromosomes in the organism. Individuals with a single copy or three copies of chromosome 4 are viable and can reproduce. A trisomic wild-type male is crossed with a disomic wild-type female: see attached image Determine the chromosome constitution and phenotypic ratios in the offspring. Assume random segregation of chromosomes into gametes.arrow_forwardDescribe the imbalance in gene products that occurs in an individual with monosomy 2.arrow_forward
- We say that genes that are close together on the same chromosome are linked. What does that mean? Imagine that in a diploid nucleus, one chromosome has the allele R and right next to it on the same chromosome is the allele T for a different gene. Are these linked? Imagine that r is right next to t on the homologous chromosome. If this cell never undergoes meiosis, does this matter at all? If it does undergo meiosis, what are the two genotypes that the gametes are most likely to have? Look at Figure for help if you need it.arrow_forwardA phenotypically normal individual has the following combinations of normal and abnormal chromosomes:The normal chromosomes are shown on the left in each pair.Suggest a series of events (breaks, translocations, crossovers, etc.)that may have produced this combination of chromosomes.arrow_forwardDraw a Punnett square for the dihybrid cross. There are two known alleles of gene occupying a specific locus in the X chromosome. The gene in question codes for a transcription factor involved in digit development. The mutant allele is dominant and gives rise to an additional but non-functioning little finger (polydactyly) on both hands. A couple have had their DNA sequenced at the region of interest, the male exhibits polydactyly because of the mutation, the female is homozygous wild type at the same locus and therefore has the wild type phenotype. Both have green eyes. In this story; eye colour shows a monogenic autosomal inheritance pattern and the allele for brown eyes shows incomplete dominance with that for blue eyes, the heterozygote phenotype is green eyes. The genes for eye colour and polydactyly show no linkage.arrow_forward
- Explain how an individual can have Down's Syndrome, and a karyotype that reveals 46 chromosomes. Group of answer choices The individual has an inversion on chromosome 21. The individual is trisomic for chromosome 21. The individual has one chromosome that is the result of a translocation. The individual is monosomic for chromosome 21. None of these is correct.arrow_forwardGiven that a human normally contains 46 chromosomes, give the chromosome number for each of the following conditions: Turner syndrome (female, no Barr bodies): Klinefelter syndrome (male, one Barr body): Triploid: Down syndrome (trisomic): Trisomy 13:arrow_forwardIn a sample of 1000 patients with Down syndrome, a geneticist discovers that 95% of them are trisomic, while 5% have diploid number of chromosomes. Explain this discrepancy.arrow_forward
- Certain varieties of chrysanthemums contain 18, 36, 54, 72, and 90 chromosomes; all are multiples of a basic set of nine chromosomes. How would you describe these varieties genetically? What feature do the karyotypes of each variety share? A variety with 27 chromosomes has been discovered, but it is sterile. Why?arrow_forwardA young couple is planning to have children. Knowing that there have been a substantial number of stillbirths, miscarriages, and fertility problems on the husband’s side of the family, they see a genetic counselor. A chromosome analysis reveals that, whereas the woman has a normal karyotype, the man possesses only 45 chromosomes and is a carrier of a Robertsonian translocation between chromosomes 22 and 13. a. List all the different types of gametes that might be produced by the man. b. What types of zygotes will develop when each of gametes produced by the man fuses with a normal gamete produced by the woman? c. If trisomies and monosomies entailing chromosomes 13 and 22 are lethal, approximately what proportion of the surviving offspring are expected to be carriers of the translocation?arrow_forwardA color-blind woman with Turner syndrome (XO) has a father who is color blind.Given that the gene for the color-blind condition is recessive and X-linked, provide a likely explanation for the origin of the color-blind and chromosome constitution in the color-blind woman. nondisjunction in the mother in meiosis I or II nondisjunction in the father at meiosis I no abnormalities had to occur to produce this daughter nondisjunction in the father in meiosis I or II nondisjunction in both the mother and father in meiosis I.arrow_forward
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