Prescott's Microbiology
10th Edition
ISBN: 9781259281594
Author: Joanne Willey, Linda Sherwood Adjunt Professor Lecturer, Christopher J. Woolverton Professor
Publisher: McGraw-Hill Education
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Chapter 12.7, Problem 3RIA
Briefly describe the pathways for triacylglycerol and phospholipid synthesis. Of what importance are phosphatidic acid and CDP-diacylglycerol?
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Phosphatidylinositol is formed using phospholipid synthesis strategy #1. Given this information, which of the following statements is true?
(A) CTP reacts with diacylglycerol.(B) Synthesis of phosphatidylinositol requires functional lipin enzyme.(C) Synthesis of phosphatidylinositol requires that the alcohol head group is activated.
(D) CDP-inositol reacts with diacylglycerol.(E) CDP-diacylglycerol reacts with inositol.
The venom of the Eastern diamondback rattler and the Indian cobra contains phospholipase A2, which catalyzes the hydrolysis of fatty acids at the C-2 position of glycerophospholipids. The phospholipid breakdownproduct of this reaction is lysolecithin (lecithin is phosphatidylcholine). At high concentrations, this and other lysophospholipids act as detergents, dissolving the membranes of erythrocytes and lysing the cells. Extensive hemolysis may be lifethreatening.(a) All detergents are amphipathic. What are the hydrophilic and hydrophobic portions of lysolecithin?(b) The pain and inflammation caused by a snake bite can be treated with certain steroids. What is the basis of this treatment?(c) Though the high levels of phospholipase A2 in venom can be deadly, this enzyme is necessary for a variety of normal metabolic processes. What are these processes?
Chapter 12 Solutions
Prescott's Microbiology
Ch. 12.1 - Prob. 1RIACh. 12.1 - Retrieve, Infer, Apply What is self-assembly? What...Ch. 12.3 - Retrieve, Infer, Apply Briefly describe the three...Ch. 12.3 - Retrieve, Infer, Apply Which two enzymes are...Ch. 12.4 - MICRO INQUIRY How might acetyl-CoA be used by the...Ch. 12.4 - Prob. 2MICh. 12.4 - MICROINQUIRY What is the difference between Lipid...Ch. 12.4 - Retrieve, Infer, Apply What is gluconeogenesis?...Ch. 12.4 - Retrieve, Infer, Apply Describe the formation of...Ch. 12.4 - Retrieve, Infer, Apply Suppose a microorganism is...
Ch. 12.4 - Retrieve, Infer, Apply Diagram the steps involved...Ch. 12.4 - Retrieve, Infer, Apply What would happen to a cell...Ch. 12.5 - What purpose is served for the cell when these...Ch. 12.5 - Prob. 2MICh. 12.5 - Prob. 1RIACh. 12.5 - How is nitrate assimilated? How does assimilatory...Ch. 12.5 - Prob. 3RIACh. 12.5 - How do organisms assimilate sulfur? How does...Ch. 12.5 - Prob. 5RIACh. 12.5 - Prob. 6RIACh. 12.5 - Describe the glyoxylate cycle. How is it similar...Ch. 12.5 - Prob. 8RIACh. 12.5 - List the types of organisms that use each...Ch. 12.6 - How is phosphorus assimilated? What roles do...Ch. 12.6 - Explain the difference between a purine and a...Ch. 12.6 - Outline the way in which purines and pyrimidines...Ch. 12.7 - Prob. 1RIACh. 12.7 - How are unsaturated fatty acids made?Ch. 12.7 - Briefly describe the pathways for triacylglycerol...Ch. 12.7 - Activated carriers participate in carbohydrate,...Ch. 12.7 - Prob. 5RIACh. 12 - What would happen if a microorganism that depended...Ch. 12 - Intermediary carriers are in a limited supply:...Ch. 12 - Magnetotactic bacteria are morphologically and...
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- Glucose 6-phosphate can be converted into a molecule of glucose 1-phosphate, which can undergo additional modification to eventually be added to a polymer of glycogen. Glycogen is simply a long, branched polysaccharide comprised of glucose subunits. The four major reactions of the glycogen synthesis pathway are listed below. Glucose 6-phosphate → Glucose 1-phosphate Glucose 1-phosphate + UTP → UDP-glucose + PPi PPi + H2O → 2 Pi UDP-glucose + Glycogenn → Glycogenn+1 + UDP glycogenn - a polymer of glycogen composed of n subunits of glucose glycogenn+1 - a polymer of glycogen composed of n+1 subunits of glucose PPi - pyrophosphate, which is an ion composed of two phosphate groups UTP - uridine triphosphate, a nucleic acid like ATP; it has three phosphate groups UDP - uridine diphosphate, identical to UTP but with two phosphate groups instead of three What is the net reaction for the four reactions shown above? Glucose 6-phosphate + UTP + Glycogenn + H2O → UDP-glucose +…arrow_forwardCan you please pick the right answer in each parentheses? Sphingolipids are synthesized from ["palmitoyl-CoA", "cholesterol"] and have a diversity of biological functions that include ["signaling", "both structural element of myelin and signaling", "structural element of myelin sheath"]. Fatty acid synthesis occurs in the ["cytoplasm", "endoplasmic reticulum"] and the delivery of ["acetyl-CoA unit as building blocks", "pyruvate"] occurs via the ["citrate shuttle", "pyruvate transporter"].arrow_forwardGlucose-1-phosphate has a higher phosphoryl group transferpotential than does glucose-6-phosphate. Review the structures of these molecules and suggest a reason for thisphenomenon.arrow_forward
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