Pearson eText for Essential Organic Chemistry -- Instant Access (Pearson+)
Pearson eText for Essential Organic Chemistry -- Instant Access (Pearson+)
3rd Edition
ISBN: 9780137533268
Author: Paula Bruice
Publisher: PEARSON+
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Chapter 11.12, Problem 22P
Interpretation Introduction

Interpretation:

The mechanism has to be written for the reaction of an amide with an alcohol in presence of an acid catalyst to give ester as a product.

Concept introduction:

The general reaction of an amide with an alcohol does not give a product. As amides are least reactive carboxylic acid derivatives so to increase the reactivity of amides a mineral acid is added. Thus reaction of alcohol and amides in presence of acid gives an ester as a product. The reaction eqaution is written as,

Pearson eText for Essential Organic Chemistry -- Instant Access (Pearson+), Chapter 11.12, Problem 22P

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