Chapter 11, Problem 10P

Interpretation Introduction

(a) Interpretation:

The equilibrium constant for the given reaction and the maximum $\frac{[glu\cos e-6-phosphate]}{[glu\cos e]}$ ratio should be calculated.

Concept introduction:

The standard Gibbs free energy change, $\Delta {\text{G}}^0$ and equilibrium constant, K are related to each other as follows:

$\Delta {\text{G}}^0=-\mathrm{RTlnK}$

Here, R is Universal gas constant and T is temperature.

For any equilibrium reaction as follows:

$\text{A}+\text{B}\rightleftharpoons \text{C}+\text{D}$

Equilibrium constant can be calculated as follows:

$\text{K}=\frac{\left[\text{C}\right]\left[\text{D}\right]}{\left[\text{A}\right]\left[\text{B}\right]}$

Here, $\left[\text{A}\right],\left[\text{B}\right],\left[\text{C}\right]\text{and}\left[\text{D}\right]$ is concentration of species A, B, C and D of the reaction.

Interpretation Introduction

(b) Interpretation:

The maximum ratio of $\frac{[glu\cos e]}{[glu\cos e-6-phosphate]}$ should be calculated for the reverse reaction.

Concept introduction:

The standard Gibbs free energy change, $\Delta {\text{G}}^0$ and equilibrium constant, K are related to each other as follows:

$\Delta {\text{G}}^0=-\mathrm{RTlnK}$

Here, R is Universal gas constant and T is temperature.

For any equilibrium reaction as follows:

$\text{A}+\text{B}\rightleftharpoons \text{C}+\text{D}$

Equilibrium constant can be calculated as follows:

$\text{K}=\frac{\left[\text{C}\right]\left[\text{D}\right]}{\left[\text{A}\right]\left[\text{B}\right]}$

Here, $\left[\text{A}\right],\left[\text{B}\right],\left[\text{C}\right]\text{and}\left[\text{D}\right]$ is concentration of species A, B, C and D of the reaction.

Interpretation Introduction

(c) Interpretation:

The conditions should be identified under which both the directions are favored in substrate cycle.

Concept introduction:

Substrate cycle is the cycle of phosphorylation & dephosphorylation which is catalyzed by two enzymes and the net effect is hydrolysis of adenosine tri phosphate which releases adenosine di phosphate, inorganic phosphate and heat generation.

Interpretation Introduction

(d) Interpretation:

Factors that control the direction of net conversion of substrate cycle such as in the cell should be identified.

Concept introduction:

Substrate cycle is the cycle of phosphorylation & dephosphorylation which is catalyzed by two enzymes and the net effect is hydrolysis of adenosine tri phosphate which releases adenosine di phosphate, inorganic phosphate and heat generation.