Biochemistry: Concepts and Connections (2nd Edition)
Biochemistry: Concepts and Connections (2nd Edition)
2nd Edition
ISBN: 9780134641621
Author: Dean R. Appling, Spencer J. Anthony-Cahill, Christopher K. Mathews
Publisher: PEARSON
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Chapter 11, Problem 3P

a. NAD+ kinase catalyzes the ATP-dependent conversion of NAD + to NADP+ . How many reducing equivalents are involved in this reaction?
b. How many reducing equivalents are involved in the conversion of ferric ion to ferrous ion?
c. How many reducing equivalents are involved in reducing one molecule of oxygen gas to water?

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(a) NAD+ kinase catalyzes the ATP-dependent conversion of NAD+ to NADP+. How many reducing equivalents are involved in this reaction? (b) How many reducing equivalents are involved in the conversion of ferric ion to ferrous ion? (c) How many reducing equivalents are involved in reducing one molecule of oxygen gas to water?
A.What is the Result of the sodium potassium ATPase activity in the cell? B.What mechanism does the sodium potassium ATPase use to achieve this result? C. Why is the above-mentioned change in affinity critical for the sodium potassium ATPase to perform its function?
Cells maintain different steady state ratios of NAD+/NADH (1000) and NADP+/NADPH (0.01). (a) How do these ratios relate to the metabolic functions of NAD+ and NADPH? (b) Given these physiological ratios, what is the AG for NAD+ to oxidize NADPH? (c) This reaction does not happen in most tissues. Make a hypothesis: what prevents this from occuring?

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