EBK MICROBIOLOGY:W/DISEASES BY BODY...-
5th Edition
ISBN: 9780134608242
Author: BAUMAN
Publisher: PEARSON
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Textbook Question
Chapter 10, Problem 4SA
Given that both human cells and pathogens synthesize proteins at ribosomal sites, how can antimicrobial agents that target this process be safe to use in humans?
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Students have asked these similar questions
Important characteristics of antimicrobial drugs include:
a) readily delivered to the site of infection
b) high toxicity against microbial cells
c) do not cause serious side effects in humans
d) remains active in body tissues and fluids
e) all of the above
Which statement among A-D is false regarding bacterial toxins?
A) O Hemolysıns are cell membrane disrupters that can rupture red blood cells.
B) O Second mesengar pathway disrupters like cholera toxin produces a debilitating respiratory condition of the lungs.
C) O Shiga toxin, tetanus toxin, and hemolysins are all types of exotoxins.
D) O Superantigens elicit a hyperactive response by the immune system and can lead to shock.
E) O None are false, A-D are all true statements.
We have many antimicrobial drugs to treat bacterial infections, but very few for viruses. Why is it so difficult to treat viral infections? Hint: What would the targets for the drugs be?
Chapter 10 Solutions
EBK MICROBIOLOGY:W/DISEASES BY BODY...-
Ch. 10 - Prob. 1TMWCh. 10 - Some antimicrobial drugs are harmful to humans....Ch. 10 - Antibiotic Overkill A young woman was taking...Ch. 10 - Prob. 2CCSCh. 10 - Prob. 3TMWCh. 10 - Why is it incorrect to say that an individual...Ch. 10 - Prob. 1EDCSCh. 10 - Prob. 3CCSCh. 10 - Prob. 1MCCh. 10 - In a Kirby-Bauer susceptibility test, the presence...
Ch. 10 - Prob. 3MCCh. 10 - Prob. 4MCCh. 10 - Cross resistance is _____. a. the deactivation of...Ch. 10 - Prob. 6MCCh. 10 - Prob. 7MCCh. 10 - Prob. 8MCCh. 10 - Prob. 9MCCh. 10 - Prob. 10MCCh. 10 - Label each figure below to indicate the class of...Ch. 10 - What specific test for antimicrobial efficacy is...Ch. 10 - What characteristics would an ideal...Ch. 10 - Prob. 2SACh. 10 - Why is the fact that drug Z destroys the NAM...Ch. 10 - Given that both human cells and pathogens...Ch. 10 - Prob. 5SACh. 10 - Prob. 6SACh. 10 - Prob. 7SACh. 10 - Prob. 8SACh. 10 - Compare and contrast the actions of polyenes,...Ch. 10 - Prob. 10SACh. 10 - Prob. 1CTCh. 10 - How does Penicillium escape the effects of the...Ch. 10 - How might a colony of Bacillus licheniformis...Ch. 10 - Fewer than 1 % of known antibiotics have any...Ch. 10 - In an issue of News of the Lepidopterists Society,...Ch. 10 - Even though aminoglycosides such as gentamicin can...Ch. 10 - Prob. 7CTCh. 10 - Prob. 8CTCh. 10 - Why might amphotericin B affect the kidneys more...Ch. 10 - Antiparasitic drugs in the benzimidazole family...Ch. 10 - Prob. 11CTCh. 10 - Scientists have cultured bacteria isolated from...Ch. 10 - Prob. 13CTCh. 10 - Prob. 14CTCh. 10 - Enterococcus faecium is frequently resistant to...Ch. 10 - Prob. 1CM
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- What bacterial structural target would make an antibacterial drug selective for gram-negative bacteria? Provide one example of an antimicrobial compound that targets this structure.arrow_forwardDefine antispasmodics.arrow_forwardThe type of antimicrobial drug that would be most likely to have toxic effects in humans based on the premise of selective toxicity when treating microbial infection would be a drug that O 1) inhibits the synthesis of the cell wall O 2) inhibits metabolic pathways O 3) disrupts the cytoplasmic membrane 4) inhibits protein synthesis 5) All of the above have equal potential to be toxicarrow_forward
- The ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes? a) Tetracycline b) Erythromycinarrow_forwardWhich definition goes with which 1) defensins 2) pentatraxins 3) bradykinin 4) psoriasis 5 ) alpha2 macroglobulinarrow_forwardis Polymyxin a cationic antimcrobial peptide? Does Aureomycin targets lipopolysaccharide?arrow_forward
- All of the following can be side effects of antimicrobialagents EXCEPT:(a) “Superinfections” can occur with new pathogens whendefensive capacity of normal flora is destroyed(b) Host toxicity(c) Disruption of normal microflora in host(d) Host allergic reaction(e) Host “superimmunity”arrow_forwardAnswer all of the questions 1. Which of the following antimicrobial drugs target DNA/RNA synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 2. Which of the following antimicrobial drugs target protein synthesis? a) Ciprofloxacin b) Sulfa drugs c) Gentamycin d) Penicilline) Polymyxin B 3. true or false: Streptococcus is killed by growing on blood agar.arrow_forwardWhere do true antibiotics come from in nature? Explain why this is the case.arrow_forward
- 3) Make the match with the terms and definitions Bioinert Undergoes degradation in the body and can be secreted naturally Bioactive Causing "no" biological effect/host response Biodegradable Produces an unexpected effect on living tissue 4) Which one of the below given properties belongs to second generation biomaterials ? a) Minimal reaction/interaction with the body b) stimulate specific cell responses at molecular level c) controlled reaction with the physiological enviroment d) Biointeractive and resorbablearrow_forwardGive detailed Solution. Don't give Ai generated solutionarrow_forwardAll the following would be of benefit to extracellular pathogens, except A) O the presence of a capsule B) O ability to prevent the fusion of a phagosome and lysosome C) O ability to prevent of opsonization D) O ability to alter cell surface proteins via phase variation E) O There are no exceptions; all are of benefit to extracellular pathogens.arrow_forward
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USMLE-Rx Antimicrobial Therapy; Author: USMLE-Rx;https://www.youtube.com/watch?v=Pka1Ynlrqtw;License: Standard Youtube License