To tell: Why physicians do not invariably prescribe the antimicrobial with the largest zone of inhibition. Introduction: The disk-diffusion test is a method applied to evaluate the antibiotic susceptibility. In petri plate (where an antibiotic disk is placed on a uniformly inoculated test pathogen), the clear area (measured in diameter) showing the absence of bacterial growth is referred to as the zone of inhibition. The minimal inhibitory concentration (MIC) is the least antibiotic concentration required to inhibit visible growth of bacteria. The minimal bactericidal concentration (MBC) is the lowest concentration of antibiotic required to kill the bacteria. But, it cannot be used to determine whether an antibiotic is bactericidal or just bacteriostatic. In order to determine MIC and MBC of an antibacterial drug, a broth dilution test is useful.

Question

Want to see the full answer?

Answer 1

Question

Chapter 10, Problem 3TMW

Summary Introduction

To tell:

Why physicians do not invariably prescribe the antimicrobial with the largest zone of inhibition.

Introduction:

The disk-diffusion test is a method applied to evaluate the antibiotic susceptibility. In petri plate (where an antibiotic disk is placed on a uniformly inoculated test pathogen), the clear area (measured in diameter) showing the absence of bacterial growth is referred to as the zone of inhibition. The minimal inhibitory concentration (MIC) is the least antibiotic concentration required to inhibit visible growth of bacteria. The minimal bactericidal concentration (MBC) is the lowest concentration of antibiotic required to kill the bacteria. But, it cannot be used to determine whether an antibiotic is bactericidal or just bacteriostatic. In order to determine MIC and MBC of an antibacterial drug, a broth dilution test is useful.

Expert Solution & Answer

Want to see the full answer?

Check out a sample textbook solution

See solution

Students have asked these similar questions

Which of the structural components listed in the Essential terms of section 1.3 (Cell components) could occur in a plant cell? Paragraph く BIUA 川くく 80 + кл K

Which of the following statements refer(s) directly to the cell theory? (Note that one or more correct answers are possible.) Select 2 correct answer(s) a) There are major differences between plant and animal cells. b) There are major differences between prokaryote and eukaryote cells. c) All cells have a cell wall. d) All cells have a cell membrane. e) Animals are composed of cells. f) When a bacterial cell divides, it produces two daughter cells.

Preoperative Diagnosis: Torn medial meniscus, left knee Postoperative Diagnosis: Combination horizontal cleavage tear/flap tear, posterior horn, medial meniscus, left knee. Operation: Arthroscopic subtotal medial meniscectomy, left knee Anesthetic: General endotracheal Description of Procedure: The patient was placed on the operating table in the supine position and general endotracheal anesthesia was administered. After an adequate level of anesthesia was achieved, the patient's left lower extremity was prepped with Betadine scrubbing solution, then draped in a sterile manner. Several sites were then infiltrated with 1% Xylocaine solution with Epinephrine to help control bleeding from stab wounds to be made at these sites. These stab wounds were made anterolaterally at the level of the superior pole of the patella for insertion of an irrigation catheter into the suprapatellar pouch area, anterolaterally at the level of the joint line for insertion of the scope and anteromedially at…