Biochemistry, The Molecular Basis of Life, 6th Edition
Biochemistry, The Molecular Basis of Life, 6th Edition
6th Edition
ISBN: 9780190259204
Author: Trudy McKee, James R. McKee
Publisher: Oxford University Press
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Chapter 1, Problem 53FB
Summary Introduction

To review:

The given blank space in the statement “Sequence changes in DNA are called____________.”

Introduction:

Deoxyribonucleic acid (DNA) is a double-stranded structure made up of sequences of nucleotides. It acts as a repository of genetic information that contains all the information that can be passed on to the future generations. It is chemically a nucleic acid, which contains complementary base pairing. Certain errors during replication or stress conditions can introduce modifications in DNA that alters its sequence.

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You’ve isolated a protein and determined that the Native molecular weight of the holoenzyme is 160 kD using size exclusion chromatography. Analysis of this protein using SDS-PAGE revealed 2 bands, one at 100 kD and one at 30 kD.  The enzyme was found to be 0.829% NAD (by weight). What further can be said regarding the structure of the polypeptide?
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